A second look at slow PSA rise

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goodlife
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Date Joined May 2009
Total Posts : 2692
   Posted 4/4/2011 9:26 PM (GMT -6)   
Two years post RP. Gleason 9, so I am staying on top of this thing. PSA less than .01 for 15 months, then a creep to .03. I believe that it is the beginning of BCR, and I have made preparations for SRT.

Today I visited with Dr. Stephenson of Cleveland Clinic. He coauthored the post SRT nomograms with MSK. Interestingly, he was not concerned with the PSA. He dialed up the nomogram, and pointed out that I was 2 years post RP without BCR, which he pointed out that statistically I had a 65 % chance of a cure. He considers .06 as BCR. Based on the numbers, he is still feeling that the PSA is benign prostate tissue.

I must admit that he made me feel little more relaxed. Come back in 3 months and we will see what the PSA is doing. Apparently they don't even try to calculate PSADT at levels below .1.

Another interesting note on their latest study said the average time from BCR to distant metastasis was 8 years. So, if I can hold off BCR for a few years with SRT, might be ok.

Goodlife

Radical
Veteran Member


Date Joined Mar 2009
Total Posts : 739
   Posted 4/4/2011 10:23 PM (GMT -6)   
Certainly very positive news, lets keep our fingers crossed..........Kev

Tony Crispino
Veteran Member


Date Joined Dec 2006
Total Posts : 8128
   Posted 4/4/2011 11:02 PM (GMT -6)   
Good deal. i like what he said.

Keep up the low numbers!

Tony
Advanced Prostate Cancer at age 44 (I am 48 now)
pT3b,N0,Mx (original PSA was 19.8) EPE, PM, SVI. Gleason 4+3=7

Treatments:
Da Vinci Surgery ~ 2/16/2007
Adjuvant Radiation Therapy ~ IMRT Completed 8/07
Adjuvant Hormone Therapy ~ 28 months on Casodex and Lupron.
Undetectable PSA.

Blog: www.caringbridge.org/visit/tonycrispino

Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25393
   Posted 4/4/2011 11:08 PM (GMT -6)   
goodlife,

sounds like encouraging words there. the rad oncologists i talked to when i had post surgery bcr, agreed that at around .05, they suspected bcr in surgery patients, but not a hard fast rule

good luck holding the beast at bay

david
Age: 58, 56 dx, PSA: 7/07 5.8, 10/08 16.3
3rd Biopsy: 9/08 7 of 7 Positive, 40-90%, Gleason 4+3
open RP: 11/08, on catheters for 101 days
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos marg
Incont & ED: None
Post Surgery PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12, 4/8 .04, 8/6 .06 2/11 1.24
Latest: 6 Corr Surgeries to Bladder Neck, SP Catheter since 10/1/9, SRT 39 Sess/72 gy ended 11/09, 21 Catheters, Ileal Conduit Surgery 9/10,

Cajun Jeff
Veteran Member


Date Joined Mar 2009
Total Posts : 4119
   Posted 4/5/2011 5:47 AM (GMT -6)   
Goodlife,

I opened your thread with fear in my heart. I think this is positive news. Will be seeing you in a little over a wk.

Cajun Jeff
9/08 PSA 5.4 referred to Urologist
9/08 Biopsy: GS 3+4=7 1 positive core in 12 1% cancer core
10/08 Nerve-Sparing open radicalSurgery Path Report Downgrade 3+3=6 GS Stage pT2c margins clea
r3 month: PSA <0.1
19th month: PSA <0.1
2 year PSA <0.1
Only issue at this time is ED but getting better

Ed C. (Old67)
Veteran Member


Date Joined Jan 2009
Total Posts : 2461
   Posted 4/5/2011 5:00 PM (GMT -6)   
Goodlife,
Being Gleason 8 myself, I always look at your posts and monitor your progress. That is good news from your Doctor. It is encouraging to have positive news from this PCs fight.
Age: 67 at Dx on 12/30/08 PSA 3.8
2 cores out of 12 were positive Gleason (4+4)
Davinci surgery 2/9/09 Gleason 4+4 EPE,
Margins clear, nerve bundles removed
Prostate weighed 57 grams 10-20% involved
all PSA tests since (2, 5, 8, 11, 15, 18, 21 months) undetectable
Latest PSA test (2 years) <.008 ?

goodlife
Veteran Member


Date Joined May 2009
Total Posts : 2692
   Posted 4/5/2011 10:21 PM (GMT -6)   
Hey Ed,

Look forward to swapping notes in Baton Rouge.

Goodlife
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