I was never fatigued after two recent surgeries. I had bypass surgery in 2005 with 5 bypasses, then a RP
open Surgery in 2008. Was back to work in 6 weeks after each one and totally amazed everyone that I work with, because I had so much energy.
However, I just finished up 39 sessions on IMRT and the last week really made me tired. I was taking a nap every day around noon and falling asleep early every night. It's been three weeks since it ended and I'm finally being able to watch TV until 10:00 PM now.
I would definitely vote for the radiation as being more difficult to deal with.