Clinical trial in my future

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Bob & Wife
Regular Member


Date Joined Apr 2008
Total Posts : 100
   Posted 4/5/2011 7:59 PM (GMT -6)   
Saw oncologist today for my rising psa after surgery and radiation. The doctor said no prostate cancer reacts the same from person to person regarding ht therapy, some will respond and drop to undetectable for extended periods of time. The doctor also said you can wait until your psa reaches 10 if you have no symptoms before starting HT. There are 2 clinical trials currently at Oregon Health Sciences University (Knight Cancer Center) for rising psa’s for patients who have rising psa’s after surgery and radiation. The doctor feels I will be eligible for one of the trials by this summer. I will have my psa drawn again at the end of June and will see the doctor July 5th to see if I qualify for one of the clinical trials.
Age at diagnosis 58 Biopsy 4+4 Surgery 2006, clear nodes and margins
2007 PSA's .14 .16.14.32 2008 Radiation complete post PSA .05 .06.18.14
2009 PSA's .06 .05 .18.14
201 PSA's .18 .19 5 wks later .34 .38
2011 PSA's .59

Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25380
   Posted 4/5/2011 8:21 PM (GMT -6)   
Bob,

What specific symptons would one be looking for after the failure of surgery and salvage radiation? Do you mean like evidence of mets?

david
Age: 58, 56 dx, PSA: 7/07 5.8, 10/08 16.3
3rd Biopsy: 9/08 7 of 7 Positive, 40-90%, Gleason 4+3
open RP: 11/08, on catheters for 101 days
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos marg
Incont & ED: None
Post Surgery PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12, 4/8 .04, 8/6 .06 2/11 1.24
Latest: 6 Corr Surgeries to Bladder Neck, SP Catheter since 10/1/9, SRT 39 Sess/72 gy ended 11/09, 21 Catheters, Ileal Conduit Surgery 9/10,

Bob & Wife
Regular Member


Date Joined Apr 2008
Total Posts : 100
   Posted 4/5/2011 8:29 PM (GMT -6)   
David,

The doctor said changes in urination or sharp pains like in the middle of your arm , pelvis area etc. like you have never experienced before. Not pains in your joints which could be arthritis. The doctor said you will know something is different and not right. I also asked how accurate the bones scans are and he said they are very accurate and with mine they picked up a lot of arthritis in my hips and spine. I too also had bladder neck surgery done years ago. Bob
Age at diagnosis 58 Biopsy 4+4 Surgery 2006, clear nodes and margins
2007 PSA's .14 .16.14.32 2008 Radiation complete post PSA .05 .06.18.14
2009 PSA's .06 .05 .18.14
201 PSA's .18 .19 5 wks later .34 .38
2011 PSA's .59
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