Predisone and PC?

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Purgatory
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Date Joined Oct 2008
Total Posts : 25393
   Posted 4/10/2011 9:22 PM (GMT -6)   
I may be getting myself confused or mixed up on this subject, so I throw it out to the crowd for an opinion.  Is Predisone used with HT, or only in conjunction with Chemo if needed in regards to PC?
 
It concerns me, because of all the meds in the world, I am extremely allergic to Predisone and its cousins.  Twenty years ago, I had an adverse reaction while on Predisone that was prescribed for a chest injury.  It took me 3 times into the ER, with heart attack symptons, and I had a difficult being free of side effects from it, even though I was on it for less than 3 weeks.  It took me more than 3 years to get over the effects.  It's listed on my medical records that I should never be put on it.
 
Could this allergy to it, be a potential worry in the future, or is it really used with advanced PC?
 
David in SC

compiler
Veteran Member


Date Joined Nov 2009
Total Posts : 7270
   Posted 4/10/2011 9:56 PM (GMT -6)   

I think I've heard of it given with various chemo regimens

 

Mel


Northfoot
Regular Member


Date Joined Mar 2011
Total Posts : 81
   Posted 4/10/2011 11:02 PM (GMT -6)   
Prednisone is given with docetaxel in order to decrease fluid retention and hypersensitivity reactions.

Northfoot
Regular Member


Date Joined Mar 2011
Total Posts : 81
   Posted 4/10/2011 11:04 PM (GMT -6)   
That's for chemotherapy, btw.

Northfoot
Regular Member


Date Joined Mar 2011
Total Posts : 81
   Posted 4/10/2011 11:04 PM (GMT -6)   
That's for chemotherapy, btw.

Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25393
   Posted 4/10/2011 11:12 PM (GMT -6)   
That was the impression I had too. Hope I never need to find out, as I would never consent to use it again.
Age: 58, 56 dx, PSA: 7/07 5.8, 10/08 16.3
3rd Biopsy: 9/08 7 of 7 Positive, 40-90%, Gleason 4+3
open RP: 11/08, on catheters for 101 days
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos marg
Incont & ED: None
Post Surgery PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12, 4/8 .04, 8/6 .06 2/11 1.24
Latest: 6 Corr Surgeries to Bladder Neck, SP Catheter since 10/1/9, SRT 39 Sess/72 gy ended 11/09, 21 Catheters, Ileal Conduit Surgery 9/10,

logoslidat
Veteran Member


Date Joined Sep 2009
Total Posts : 6085
   Posted 4/11/2011 12:17 AM (GMT -6)   
I,m sitting here with a 9 day regimen for predisone as we speak. Its for a pinched nerve radiculapthy recurrence had it before, but really didn't like it . I will probably pass and use the old spine inverter.
Diagnosed 8/14/09 psa 8.1 66,now 67
2cores 70%, rest 6-7 < 5%
gleason 3+ 3, up to 3+4 @ the dub
RPP U of Wash, Bruce Dalkin,
pathology 4+3, tertiary5, 2 foci
extensive pni, prostate confined,27 nodes removed -, svi - margins -
99%continent@ cath removal. 1% incont@gaspass,sneeze,cough 18 mos, squirt @ running. psa std test reported on paper as 0.0 as of 12/14/10 ed improving

zufus
Veteran Member


Date Joined Dec 2008
Total Posts : 3149
   Posted 4/11/2011 6:55 AM (GMT -6)   
It is used for Ketoconazole useage, Abiraterone (Zytiga brand name) and I think TAK700. Those have alot of similarities.
------------------------------------------------------------------------------------------------
New drug MDV3100 looks like it is being trumped already by ARN-509 (Aragon Pharma) it is more potent than MDV3100 (aka 'super casodex'). ARN-509 is in clinical trials Phase I/II and already looks more potent and perhaps better. These two drugs don't use Predisone, fyi.
 
Purg-perhaps if you look into therapies, maybe staying away from Prednisone would be good, there are still lots of choices to look into...some docs won't mention any of them...so you might need to be proactive is a suggestion.

Post Edited (zufus) : 4/11/2011 5:58:37 AM (GMT-6)


Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25393
   Posted 4/11/2011 8:21 AM (GMT -6)   
zufus, if i were ever on the chemo type treatments, i still wouldnt consent to predisone again, i would have to find an alternative
Age: 58, 56 dx, PSA: 7/07 5.8, 10/08 16.3
3rd Biopsy: 9/08 7 of 7 Positive, 40-90%, Gleason 4+3
open RP: 11/08, on catheters for 101 days
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos marg
Incont & ED: None
Post Surgery PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12, 4/8 .04, 8/6 .06 2/11 1.24
Latest: 6 Corr Surgeries to Bladder Neck, SP Catheter since 10/1/9, SRT 39 Sess/72 gy ended 11/09, 21 Catheters, Ileal Conduit Surgery 9/10,
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