I think I've asked this before but don't remember getting an answer.
We know that a fast PSADT is bad news, pointing the an aggressive cancer. We also know that HT varies in it's effectiveness, from 0 months to 10 years at the two extremes.
Can one conclude that a fast PSADT implies HT will only work for a brief time? It seems logical, but I have not read of any predictors on how well HT will work (there may be some at the genetic/molecular level).
It would be encouraging, for those of us with fast PSASDT, to hear that this has no bearing on predicting HT failure.
PSA-- 3/08--2.90; 8/09--4.01; 11/09--4.19 (PSAf: 24%), PCA3 =75 .Biopsy 11/30/09. Gleason 4+3. Age: 64. Surgery: Dr. Menon @Ford Hospital, 1/26/10. Pathology Report: G 4+3. Nodes: Clear. PNI: yes. SVI: No. EPE: yes. Pos. Margin: Yes-- focal-- 1 spot .5mm. 100% continent by 3/10. ED- yes.. PSA on 3/10/10-: 0.01. PSA on 6/21/10--0.02. 9/21/10--0.06; 1/4/11-0.13,3/1/11--0.27. Now doing SRT