Jerry L. said...
With a PSA of .09 and hot spot on scan, it's fairly obvious that my PSA is a bad spokesperson for my PC.
I realize scans can monitor specific areas, but is there any other ways to monitor the level of all of the PC globally?
How am I to judge if therapies are working?
PSA will be still the main test to monitor. Others have mention tests that indicate if the cancer has a neuroendocrine character (such PCa tumors might make little PSA while progressing). A baseline of both neuron-specific enolase (NSE) and chromogranin A (CGA) could help to avoid that situation.
Other important markers to follow are prostate acid phosphatase (PAP) and Alkaline Phosphatase (AlkP). These tests measure potential bone involvement which is a common met site.
Continue relying on PSA as your primary marker. Relying on a super-sensitive PSA test can have some benefit for surgical patients and those who had salvage therapy.
Surviving prostate cancer since 1992. RP; Orchiectomy;
GS (4 + 2); bilateral seminal vesicle invasion; tumor attached to rectal wall. Last PSA September, 2010: <0.1 ng/ml
Laughter is the best medicine!