BCR and morbidity

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reachout
Veteran Member


Date Joined May 2009
Total Posts : 725
   Posted 4/16/2011 1:36 PM (GMT -6)   
If this was posted, I guess I missed it. It's a good news article for those with BCR, in a morbid sort of way. To those with BCR, the bad news is your prostate cancer has come back. The good news is that something else will probably kill you first. Hey, I'll take any good news with this crappy disease.

http://www.medwire-news.md/381/88857/Prostate_Cancer/Prostate_cancer_death_related_to_BCR,_but_rare_outcome_.html
Age: 66
PSA: 7 tests over 2 years bounced around from 2.6 to 5.6
Biopsy 8 of 12 positive, Gleason 3+4, T2a
DaVinci August 2009, pathology Gleason 4+3, neg margins, T2c
Continent right away, ED
Viagra, Cialis did't work, Trimix works well
Post-surgery PSA:
3, month: undetectable <.1; 6 month: undetectable <.014 (ultrasensitive); 9, 12, 15 month: undetectable <.1; 18 month detectable .05

runner48
Regular Member


Date Joined Mar 2011
Total Posts : 26
   Posted 4/16/2011 3:27 PM (GMT -6)   
Thanks for posting this reachout. I'm like you.. looking for any silver lining I can find!
Psa 4.1 2/2011
Biopsy 2 cores out of 12 positive, Gleason 6
Robotic Prostatectomy 4/2011
Post-Op: pT2c, Gleason 6, 2 tumors in 10% of prostate, seminal vesicles neg, focal areas PNI seen, carcinoma focally extends to the inked margin in left apex, no extension through prostate capsule into periostatic soft tissue.

Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25380
   Posted 4/16/2011 5:02 PM (GMT -6)   
reachout:

good article, but note closely what it said:

"although only a minority of elderly men with recurrence will die from the disease"

The article went on to say that the average age of the patient was 70.

Not sure how much of the good news would still be applicable to someone that is only in their 40-50w with recurrance.


David in SC
Age: 58, 56 dx, PSA: 7/07 5.8, 10/08 16.3
3rd Biopsy: 9/08 7 of 7 Positive, 40-90%, Gleason 4+3
open RP: 11/08, on catheters for 101 days
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Incont & ED: None
Post Surgery PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12, 4/8 .04, 8/6 .06, 2/11 1.24, 4/11 3.81
Latest: 6 Corr Surgeries to Bladder Neck, SP Catheter since 10/1/9, SRT 39 Sess/72 gy ended 11/09, 21 Catheters, Ileal Conduit Surgery 9/10

reachout
Veteran Member


Date Joined May 2009
Total Posts : 725
   Posted 4/16/2011 6:22 PM (GMT -6)   
David, good point. On the other hand, the article says
"By contrast, in RP and RT patients who did experience BCR, 5-, 10-, and 15-year cumulative mortality rates were 3%, 11%, and 21%, and 11%, 20%, and 42%, respectively."

So at 15 years, "only" 21% of RP patients with BCR had died. That means 4 out of 5 had not, which are pretty good odds. Sure, these were older men but if 4 out of 5 were still fighting PC off at their age, I would think a 40 or 50 year old's stronger system would fight it off even better. And they may have fought it off for much longer, the study just cut off at 15 years.

I don't know about you, but 15 years to me is sort of an infinite horizon, no matter the age. I'm 66 now and I don't really relish the idea of being around in my 80s and 90s with all the issues that entails, though I realize there are many men that age who are very agile. I felt the same when I was 50, 65 was way in the future to me. Maybe once we pass prime child rearing age we begin to put older age in perspective.
Age: 66
PSA: 7 tests over 2 years bounced around from 2.6 to 5.6
Biopsy 8 of 12 positive, Gleason 3+4, T2a
DaVinci August 2009, pathology Gleason 4+3, neg margins, T2c
Continent right away, ED
Viagra, Cialis did't work, Trimix works well
Post-surgery PSA:
3, month: undetectable <.1; 6 month: undetectable <.014 (ultrasensitive); 9, 12, 15 month: undetectable <.1; 18 month detectable .05

Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25380
   Posted 4/16/2011 6:27 PM (GMT -6)   
Some good counterpoints, reachout.

In my own case, the subject is rather mute at this point, having bcr 9 months after surgery, then srt, and now reccurance again about 9 months after that.

At 58, I look at all differently, as I am sure our brothers with PC in their 40's do as well.

Still all in all, good information

david
Age: 58, 56 dx, PSA: 7/07 5.8, 10/08 16.3
3rd Biopsy: 9/08 7 of 7 Positive, 40-90%, Gleason 4+3
open RP: 11/08, on catheters for 101 days
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Incont & ED: None
Post Surgery PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12, 4/8 .04, 8/6 .06, 2/11 1.24, 4/11 3.81
Latest: 6 Corr Surgeries to Bladder Neck, SP Catheter since 10/1/9, SRT 39 Sess/72 gy ended 11/09, 21 Catheters, Ileal Conduit Surgery 9/10

Ed C. (Old67)
Veteran Member


Date Joined Jan 2009
Total Posts : 2458
   Posted 4/16/2011 8:25 PM (GMT -6)   
At the age of almost 70 I'll take 10 years and call it a night. Death doesn't really scare me, what does scare me is what comes before it happens. I wouldn't mind a a quick heart attack. My brother had PCa and died at the age of 70 from a massive heart attack.
Age: 67 at Dx on 12/30/08 PSA 3.8
2 cores out of 12 were positive Gleason (4+4)
Davinci surgery 2/9/09 Gleason 4+4 EPE,
Margins clear, nerve bundles removed
Prostate weighed 57 grams 10-20% involved
all PSA tests since (2, 5, 8, 11, 15, 18, 21 months) undetectable
Latest PSA test (2 years) <.008 ?

Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25380
   Posted 4/16/2011 9:09 PM (GMT -6)   
Ed, sorry for the loss of your brother, but it sounds quick and merdiful at the same time.
Age: 58, 56 dx, PSA: 7/07 5.8, 10/08 16.3
3rd Biopsy: 9/08 7 of 7 Positive, 40-90%, Gleason 4+3
open RP: 11/08, on catheters for 101 days
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Incont & ED: None
Post Surgery PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12, 4/8 .04, 8/6 .06, 2/11 1.24, 4/11 3.81
Latest: 6 Corr Surgeries to Bladder Neck, SP Catheter since 10/1/9, SRT 39 Sess/72 gy ended 11/09, 21 Catheters, Ileal Conduit Surgery 9/10
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