Headaches after Trimix

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New Member

Date Joined Apr 2011
Total Posts : 1
   Posted 4/18/2011 2:55 PM (GMT -6)   
I've gotten a ton of good info from this forum, and hope to get some feedback on a problem I think I'm having with Trimix.  I've only tried the injection twice, but from the first, I've had almost constant low grade headaches which are only eased with high dose Motrin.  I rarely had headaches prior to using the Trimix.  They seem to ease after a few days with no injections or sexual activity.  I'm not sure if it's the Trimix or the effort put into achieving climax that is the cause.  I'm using the recommended dose of .20, and so far haven't really been overjoyed with the results.  The last injection gave me about 90% right off the bat and then in about 10 min. it fizzled.  My uro said I could go up to .30, but with the headaches, I'm not sure if that would be wise.  Anyone else having a similar reaction?

James C.
Veteran Member

Date Joined Aug 2007
Total Posts : 4462
   Posted 4/18/2011 3:11 PM (GMT -6)   
tkw, thanks for delurking, welcome to the Forum. I haven't had any experiences with headaches, but others may have. They will probably drop in sometime. In the meantime, I hope you stay with us.
James C., Age 64, Kingsport, E. TN
Gonna Make Myself A Better Man tinyurl.com/28e8qcg
4/07: PSA 7.6, 7/07 Biopsy: 3 of 16 PCa, 5% involved, left lobe, GS6
9/07: Nerve Sparing open RP, Path: pT2c, 110 gms., clear except:
Probable microscopic involvement-left apical margin -GS6
3 Years: PSA's .04 each test until 04/10-.06, 09/10-.09, 12/10-.09, 02/11-.08
ED-total-Bimix 30cc

Veteran Member

Date Joined Jul 2006
Total Posts : 669
   Posted 4/19/2011 8:00 AM (GMT -6)   
If you do a search, you will find that a large number of men who use trimix have headaches and or other pain problems. Pain is very common.   It comes from ther Alprostadil component of the mix.  Alprostadil also marketed as Caverject is eliminated when you use a "bimix".  The bimix has papaverine and phentolimine usually in a 30-1 mix.  It works well for many men without the pain.  It works for me.
PSA July 2006 4.7 , Nodule found
biopsy 10/06 very agressive gleason4+4=8 identified
DaVinci surgery, January 2007
Post Ob confirms, gleason 4+4=8 with no extension or invasion
no long term continence problems
post surgery PSA continues to be undetectable at 4 years
ED problems continue, using bimix
born 1941
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