The recent posts and discussions regarding those that should consider ART and those that will benefit most from ART are very interesting and informative. Of course I am reading them with interest because I am a pT3b. Thank you very much for that discussion.
Basically, I am having a difficult time understanding how one can have both negative margins and EPE. It seems to me that if one has EPE, in my case to the right bladder neck, and clear margins of resection then the EPE is irrelevant.
Therefore why would a guy with clear margins still be at increased risk of BCR if he has EPE? It seems the research indicates increased risk of BCR with EPE even with negative margins.
Also, during my surgery, the Uro/surgeon cut a urethra sample and a bladder neck sample for post-OP biopsy to make sure that the margins of resection were clear. In my case they were both benign.
Age 58 @ DX; da Vinci on 1/26/2011
PSA History: 10/2005 = 1.7; 10/2007 = 2.8; 10/2009 = 3.6; 10/2010 = 4.9
Abnormal DRE in 2009; Increasingly abnormal DRE in 2010
Thank you POPs!
Biopsy 11/2010: GS = 3+4; 5 of 12 cores pos @ 40%
Post-OP pathology: GS=3+4; tumor = 35%; pT3b; SVI+; EPE+ R. bladder neck; margins neg.
Post-OP PSA 4/13/11 = <0.1