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Regular Member

Date Joined Feb 2011
Total Posts : 45
   Posted 5/9/2011 2:04 PM (GMT -6)   
Clear margins after robotic prostatectomy.  So can I give a sigh of relief? 
I'd like to hear from other clear margin guys.  Hubby has to take first PSA in a month.
Thank you.

Veteran Member

Date Joined May 2009
Total Posts : 739
   Posted 5/9/2011 3:00 PM (GMT -6)   
I had clear margins and yes, you can definitely give a sigh of relief. I don't know your husband's numbers but with negative margins, and assuming no involvement in the lymph nodes or seminal vesicles, he should expect an undetectable PSA hopefully forever. However, in a minority of cases, the PSA may begin to rise after some time, which could be 5 years or more. In my case I've gotten a small rise after 18 months, and am back watching my PSA. So he's not out of the woods yet (none of us are) but negative margins is the first major hurdle. Congratulations!
Age: 66
PSA: 7 tests over 2 years bounced around from 2.6 to 5.6
Biopsy 8 of 12 positive, Gleason 3+4, T2a
DaVinci August 2009, pathology Gleason 4+3, neg margins, T2c
Continent right away, ED
Viagra, Cialis did't work, Trimix works well
Post-surgery PSA:
3, month: undetectable <.1; 6 month: undetectable <.014 (ultrasensitive); 9, 12, 15 month: undetectable <.1; 18 month detectable .05

Cajun Jeff
Veteran Member

Date Joined Mar 2009
Total Posts : 4119
   Posted 5/9/2011 3:14 PM (GMT -6)   
Yep Clear margins is exactly what you want to hear after the surgery. So far 2.5 years out and still in the zero club. Get my next PSA this wk.

Cajun Jeff
9/08 PSA 5.4 referred to Urologist
9/08 Biopsy: GS 3+4=7 1 positive core in 12 1% cancer core
10/08 Nerve-Sparing open radicalSurgery Path Report Downgrade 3+3=6 GS Stage pT2c margins clea
r3 month: PSA <0.1
19th month: PSA <0.1
2 year PSA <0.1
Only issue at this time is ED but getting better

Veteran Member

Date Joined Jan 2010
Total Posts : 1011
   Posted 5/9/2011 3:19 PM (GMT -6)   
I agree with reachout. Clear margins are a "clear" sign that PCa many be gone for good, given that the tumor otherwise appears capsule contained. It is a reason to celebrate. However, gleason score also works into the equations. The prognosis is much better if the pathology shows the tumor to be a G6 rather that a G8-10. Congratulations.
Dx PCa Dec 2008 at 56, PSA 3.4
Biopsy: T1c, Geason 7 (3+4) - 8 cores, 4 positive, 30% of all 4 cores.
Robotic RP March 2009
Pathology Report: T2c, Geason 8, organ confined, negitive margins, lymph nodes - tumor volume 9%, nerves spared, no negitive side effects.
PSA's < .01, .01, .07, .28, .50. ADT 3 5/10. IMRT 7/10.
PSA's post HT .01, < .01
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