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Oncas
Regular Member


Date Joined Jan 2009
Total Posts : 390
   Posted 5/11/2011 4:02 AM (GMT -6)   
Perhaps this has been discussed before. Is this new imaging proceedure being done at the Sand Lake facility in Orlando available to anyone now or is it still in a trial mode? I understand that it is superior to a prostascint at finding malignant lymph nodes. Is it also capable of detecting bone mets? Has anyone on this board had it done?
 
Jim

Age 61
Northeastern Penna.
11/08/08 annual checkup (3 yrs late) PSA 8.04 from previously 2.7 in 11/05
1/23/09 biopsy 12 cores positive, 10 cores Gleason 7, 2 cores Gleason 8 70% tumor
2/06/09 cat +bone scans clean ..
3/26/09 RRP surgery Post op path .. upgraded to Gleason 9 (5+4), seminal vesicles involved, several positive margins, 2 of 9 lymph nodes positive.

80% involved
4/4/09 Dr. advising wait for significant rise in PSA and start hormonal treatment.

1st post op at 4 weeks PSA .6 urologist concerned

will retest in one month

8/15/09 bone and pelvic scans redone .. clean PSA .65

onc/radiologist recommending starting radiation treatments and 6 month shot of Lupron .. decided against this gameplan

9/11/09 consulting with med/onc today .. not impressed
My urologist now suggesting prostascint scan

Prostascint test done at U of Penna indicates cancer still confined to prostate bed.

PSA at .7
Gonna need a bigger boat .. found a good rad oncologist

10/21/09 Rad onc suggesting clinical trial of samarium 153 followed by IMRT

2/1/10 Samarium trial completed PSA 1.0

2/1/10 began IMRT 39 treatments 70 Gy

3/25/10 finished IMRT

4/28/10 PSA .93

7/23/10 PSA 1.2

zufus
Veteran Member


Date Joined Dec 2008
Total Posts : 3149
   Posted 5/11/2011 4:30 AM (GMT -6)   
Here is what little I know on it: USPIO Ultrasmall-Superparamagnetic Iron Oxide
(was an article in NEJofMedicine of this) as from P63 in Dr. Strum's book (that many people disregard). The assessment of lymphnodes measuring 5-10mm the accurancy rate stated is 98.9% with sensitivity rated 96.4% and specificity of 99.3% (??-to us lay people sounds pretty good). Even in lymphnodes <5mm, was found to have a specificity rate of 98.1%.

This is comparable to the Combidex scanning method from Netherlands (Holland), that John T has done and was definitively proven in his case as vastly superior..John will say something on that.
 
Link to info on such:  http://www.ncbi.nlm.gov/pmc/articles/PMC30871831 (Link is NFG for some reason)  Go to www.google.com  and search for USPIO imaging for stuff.

The Doctors name in Florida on this is Dr. Bravo and we have a patient or two from another forum whom just went down there, if I find info will post it here soon.
I talked to Dr. Strum in an email about a few things recently, this scanning method was one of them. He and Dr. Barrantz (Holland scan doc) have seen images from this Florida docs lab.....they both contend (his words), that this scan is not as definitivel in clarity, but is still a good choice...and would likely be superior to anything else the US has currently to offer. (back in 2005 USPIO was awaiting FDA approval, the FDA shot down Combidex scan a few years back, Ralph Blum was at the hearings and mentioned it in a book).

Good luck in what you can find out on this, many need to know. Me always curious.

Post Edited (zufus) : 5/11/2011 4:50:00 AM (GMT-6)

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