New Test Detects PC...

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Veteran Member

Date Joined Jul 2010
Total Posts : 3596
   Posted 5/11/2011 4:03 PM (GMT -6)   
Here is another genetically based test to detect prostate cancer.. It's on the market NOW...This could be useful with men with high PSA scores but a negative biopsy..(like me)
Age 68.
PSA age 55: 3.5, DRE normal.
age 58: 4.5
61: 5.2
64: 7.5, DRE "Abnormal"
65: 8.5, " normal", biopsy, 12 core, negative...
66 9.0 "normal", 2ed biopsy, negative, BPH, Proscar
67 4.5 DRE "normal"
68 7.0 3rd biopsy positive, 4 out of 12, G-6,7, 9
RALP Sept 3 2010, pos margin, one pos vesicle nodes neg. Post Op PSA 0.9 SRT, HT. 2-15-'11 PSA 0.0

Post Edited (Fairwind) : 5/11/2011 4:06:38 PM (GMT-6)

Regular Member

Date Joined Nov 2009
Total Posts : 43
   Posted 5/11/2011 6:44 PM (GMT -6)   
I just had the test. It seems meaningful if it gives you a negative outcome, that is, if there is no mutation in your dna mitochondria indicating pca; then you have 92% chance of no pca on a second biopsy. But if it is positive -- which seems to be the standard outcome -- all it means is that you have a 25 % chance of a getting a positive result on a second biopsy, and that some time in your life, you will get pca. Well, the probability of getting a positive result on biopsy after a negative initial biopsy is significant anyway, and most guys will get pca if they live long enough. So this test does not seem to say much, even though it will cost your insurer a few thousand bucks.

After four negative biopsies, including a saturation biopsy, and a negative endorectal mri, I took the test and came out positive. But I don’t see anything clinically useful here. If anybody else sees anything more here, I would sure be interested in knowing. (Check out Fairwind's link.)

Veteran Member

Date Joined Jul 2010
Total Posts : 3596
   Posted 5/11/2011 7:46 PM (GMT -6)   
Three large, they never mention that part...I took part in a trial for a test called "Four Gene Signature Urine Test". It has proved itself to be VERY sensitive in it's ability to detect PC, two big labs hold licenses to perform the test, but it's not being marketed.. I suspect, backstage, it's all about the patents and dollars as there are similar, competing tests in the pipeline..
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