Beginning "Off Cycle" for HT

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Skate
Regular Member


Date Joined Oct 2010
Total Posts : 424
   Posted 5/12/2011 10:17 PM (GMT -6)   
Hi All:
Went to see my uro / onc today to receive my blood test results after 6 months on Zoladex. PSA <0.04 and T level 0.8, down somewhat from 3 months ago when my PSA was the same but T was 1.0. The decision was to begin a hormone vacation ("Off Cycle") now and monitor my PSA and T levels carefully. He agreed this was earlier than his usual protocal, but felt that I responded so quickly and so well on Zoladex that the timing was right. As I am on Intermittent HT, I am hoping this "Off Cycle" will last as long as possible. I couldn't have agreed more with this joint decision.  I feel wonderful right now!
Jack

Post Edited (Skate) : 5/13/2011 5:32:34 AM (GMT-6)


Cajun Jeff
Veteran Member


Date Joined Mar 2009
Total Posts : 4126
   Posted 5/12/2011 10:24 PM (GMT -6)   
Skate: Congrats on the Ht VACATION....

Cajun Jeff
9/08 PSA 5.4 referred to Urologist
9/08 Biopsy: GS 3+4=7 1 positive core in 12 1% cancer core
10/08 Nerve-Sparing open radicalSurgery Path Report Downgrade 3+3=6 GS Stage pT2c margins clea
r3 month: PSA <0.1
19th month: PSA <0.1
2 year PSA <0.1
Only issue at this time is ED but getting better

Tony Crispino
Veteran Member


Date Joined Dec 2006
Total Posts : 8128
   Posted 5/12/2011 10:28 PM (GMT -6)   
Jack,
It takes time but watch out for those old good time feelings again. But feeling good right now is a great start. I feel way better than when I did when I stopped HT but I wasn't complaining anymore at that point.

Get your T back and show up clean...just a personal request...Good Job!

Tony
Advanced Prostate Cancer at age 44 (I am 48 now)
pT3b,N0,Mx (original PSA was 19.8) EPE, PM, SVI. Gleason 4+3=7

Treatments:
Da Vinci Surgery ~ 2/16/2007
Adjuvant Radiation Therapy ~ IMRT Completed 8/07
Adjuvant Hormone Therapy ~ 28 months on Casodex and Lupron.
Undetectable PSA.

Blog: www.caringbridge.org/visit/tonycrispino

Skate
Regular Member


Date Joined Oct 2010
Total Posts : 424
   Posted 5/12/2011 10:38 PM (GMT -6)   

Thanks Guys!

J


Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25394
   Posted 5/12/2011 11:23 PM (GMT -6)   
Jack, enjoy that "vacation", you deserve it

david in sc
Age: 58, 56 dx, PSA: 7/07 5.8, 10/08 16.3
3rd Biopsy: 9/08 7 of 7 Positive, 40-90%, Gleason 4+3
open RP: 11/08, on catheters for 101 days
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Incont & ED: None
Post Surgery PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12, 4/8 .04, 8/6 .06, 2/11 1.24, 4/11 3.81
Latest: 6 Corr Surgeries to Bladder Neck, SP Catheter since 10/1/9, SRT 39 Sess/72 gy ended 11/09, 21 Catheters, Ileal Conduit Surgery 9/10

Herophilus
Veteran Member


Date Joined Sep 2009
Total Posts : 664
   Posted 5/13/2011 6:46 AM (GMT -6)   
Best of luck,
Hero....(another Jack)
Age 51 PSA 6.8
Bxy 10 of 12 Cores positive for Gleason 6. up to 75%
Robotic surg 11-02-09
Post op path. 20% neoplasm;4+3=7 Gleason
All nodes (14) and other related tissue negative for cancer
No EPE
Post op PSA x 3, all <0.01
walkbobwithjack.blogspot.com

Skate
Regular Member


Date Joined Oct 2010
Total Posts : 424
   Posted 5/13/2011 7:09 AM (GMT -6)   

Thanks Hero and David.  David you deserve results like this somewhere in that long journey of yours. That too may be in your near future.

Just Jack


zufus
Veteran Member


Date Joined Dec 2008
Total Posts : 3149
   Posted 5/13/2011 7:19 AM (GMT -6)   
Looks like great numbers, that T level is beyond just good, it is excellent for using that drug. You may have a really long off cycle and maybe get luckier than blank, probably should test in 3 months to see if it moves at all....likely it shouldn't based upon such numbers. I guess you can do a triple sokowe skating with that? (lol)

Skate
Regular Member


Date Joined Oct 2010
Total Posts : 424
   Posted 5/13/2011 7:31 AM (GMT -6)   

Zufus:

That might be kind of difficult in Hockey Skates.  I do know what that triple is as both of my daughters figure skated for many years.  It was expensive but certainly cheaper than bail. Yes we plan on testing same every three months watching for any pattern.  Hopefully none will be found for a very long time, but I am sure this will creep back into my life before too long.  Will cross that bridge when I get there.  Thanks for your kind words.

Just jack


zufus
Veteran Member


Date Joined Dec 2008
Total Posts : 3149
   Posted 5/13/2011 11:45 AM (GMT -6)   
You would look great on gracious hockey skates (lol). 'Cheaper than bail'...that was funny. You are very welcome for the words. Don't forget about the guys herein.

Went to a fight and a hockey game broke out.

I see our Detroit 'Dead Wings' came up short (lol)....actually they are amazing almost every year in recent history. It was a good series I missed that last game, but what the puck it happens.

Enjoy life asap.

ralfinaz
Veteran Member


Date Joined Jan 2011
Total Posts : 735
   Posted 5/13/2011 12:27 PM (GMT -6)   
zufus said...
Looks like great numbers, that T level is beyond just good, it is excellent for using that drug. You may have a really long off cycle and maybe get luckier than blank, probably should test in 3 months to see if it moves at all....likely it shouldn't based upon such numbers. I guess you can do a triple sokowe skating with that? (lol)


I think Skate's T level is a little high although at the castrate level of the designed LHRH used. Zufus, he reports level in nmols and not in ng. Still, it is time to enjoy his vacation and many low future PSAs

RalphV
Phoenix, Arizona
Surviving prostate cancer since 1992. RP; Orchiectomy;
GS (4 + 2); bilateral seminal vesicle invasion; tumor attached to rectal wall. Last PSA September, 2010: <0.1 ng/ml
Laughter is the best medicine!
www.pcainaz.org/phpBB304

zufus
Veteran Member


Date Joined Dec 2008
Total Posts : 3149
   Posted 5/13/2011 12:47 PM (GMT -6)   
No wonder I don't think I ever saw a T level near that low, less than <20 is considered a non-detectable T level area with LHRH, correct? So I am surprized the doc measured in nmols vs. ng like we see on our lab test reports...good note Ralph.

ralfinaz
Veteran Member


Date Joined Jan 2011
Total Posts : 735
   Posted 5/13/2011 1:00 PM (GMT -6)   
All LHRH agonists list <50 ng/dL or <1.734 nmol/L as castrate testosterone level for their products. Most experts recommend <20 ng/dL or <0.69 nmol/L as the preferred level for optimal results.

RalphV
Phoenix, Arizona
Surviving prostate cancer since 1992. RP; Orchiectomy;
GS (4 + 2); bilateral seminal vesicle invasion; tumor attached to rectal wall. Last PSA September, 2010: <0.1 ng/ml
Laughter is the best medicine!
www.pcainaz.org/phpBB304

Skate
Regular Member


Date Joined Oct 2010
Total Posts : 424
   Posted 5/13/2011 1:16 PM (GMT -6)   

Yes Zufus.  This has been great hockey this series, so far.  My eyes are still on Vancouver. Have to be as I am a Canuck!

j


leeanglo
Regular Member


Date Joined Dec 2010
Total Posts : 191
   Posted 5/15/2011 4:18 AM (GMT -6)   
Well done Jack i know how important this ht break is to you so enjoy every minute and i trulely hope you keep the numbers down for a long long time.
psa on dx 144, gleason 4+3 7 12 biopsie cores cancerous
T3a N2 M1.
psa after 3 months zoladex 20
T levels 0.5 after 3 months zoladex.
now taking 50mg cosadex daily also.

BB_Fan
Veteran Member


Date Joined Jan 2010
Total Posts : 1011
   Posted 5/15/2011 7:10 AM (GMT -6)   
Enjoy the vacation. Hope it is a good long one.
Dx PCa Dec 2008 at 56, PSA 3.4
Biopsy: T1c, Geason 7 (3+4) - 8 cores, 4 positive, 30% of all 4 cores.
Robotic RP March 2009
Pathology Report: T2c, Geason 8, organ confined, negitive margins, lymph nodes - tumor volume 9%, nerves spared, no negitive side effects.
PSA's < .01, .01, .07, .28, .50. ADT 3 5/10. IMRT 7/10.
PSA's post HT .01, < .01

Skate
Regular Member


Date Joined Oct 2010
Total Posts : 424
   Posted 5/15/2011 7:28 PM (GMT -6)   

It will be only a vacation from ADT, but I still plan on being part of this forum as it has been invaluable to me, not only in a supportive manner but also in a highly informative resource.  We are all fighting the same enemy on a variety of battlefronts and every victory is a victory for all. Let's hang in there together guys.

Jack


Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25394
   Posted 5/16/2011 12:43 PM (GMT -6)   
You are exactly correct, Jack, I fully agree
Age: 58, 56 dx, PSA: 7/07 5.8, 10/08 16.3
3rd Biopsy: 9/08 7 of 7 Positive, 40-90%, Gleason 4+3
open RP: 11/08, on catheters for 101 days
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Incont & ED: None
Post Surgery PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12, 4/8 .04, 8/6 .06, 2/11 1.24, 4/11 3.81
Latest: 6 Corr Surgeries to Bladder Neck, SP Catheter since 10/1/9, SRT 39 Sess/72 gy ended 11/09, 21 Catheters, Ileal Conduit Surgery 9/10
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