aggressive PCa protein found - McMaster scientists - article

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

tatt2man
Veteran Member


Date Joined Jan 2010
Total Posts : 2842
   Posted 5/14/2011 5:30 AM (GMT -6)   
encouraging breakthrough in PCa diagnosis -which PCa will be aggressive and grow and what will stay within the prostate -
Tang said...
“This research could serve a diagnostic purpose in terms of likelihood of whether prostate cancers at early stages will progress into metastatic tumours,”

www.thespec.com/living/healthfitness/article/529938--mcmaster-scientists-find-protein-s-role-in-prostate-cancer

Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25380
   Posted 5/14/2011 8:44 AM (GMT -6)   
very interesting, thanks
Age: 58, 56 dx, PSA: 7/07 5.8, 10/08 16.3
3rd Biopsy: 9/08 7 of 7 Positive, 40-90%, Gleason 4+3
open RP: 11/08, on catheters for 101 days
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Incont & ED: None
Post Surgery PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12, 4/8 .04, 8/6 .06, 2/11 1.24, 4/11 3.81
Latest: 6 Corr Surgeries to Bladder Neck, SP Catheter since 10/1/9, SRT 39 Sess/72 gy ended 11/09, 21 Catheters, Ileal Conduit Surgery 9/10

tatt2man
Veteran Member


Date Joined Jan 2010
Total Posts : 2842
   Posted 5/14/2011 7:00 PM (GMT -6)   
was pleased to see this article - could lead to more managed treatments and lessen the "knee-jerk" response with the reduction of the number of "variables unknown"- and improve the more pro-active treatment for those who need to hit the disease head-on.

"hugs",
BRONSON
Age:55 -gay with spouse of 14 years, Steve -Peterborough, Ontario, Canada
PSA:10/06/09 3.86
Biopsy:10/16/09- 2 of 12 cancerous, 5% involvement -Gleason 7 (3+4)
Radical Prostatectomy:11/18/09
Pathology:pT3a -Gleason 7 -extraprostatic extension -perineural invasion -prostate weight -34.1 gm
PSA:04/08/10 -0.05 -Zero Club
PSA:09/23/10 -0.05 -Zero Club
PSA:03/24/11 -0.02 -Zero Club
PSA:03/24/12- TBA

Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25380
   Posted 5/14/2011 8:14 PM (GMT -6)   
bronson,

sorry i missed you on chat night, i was in and out a few times.

david
Age: 58, 56 dx, PSA: 7/07 5.8, 10/08 16.3
3rd Biopsy: 9/08 7 of 7 Positive, 40-90%, Gleason 4+3
open RP: 11/08, on catheters for 101 days
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Incont & ED: None
Post Surgery PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12, 4/8 .04, 8/6 .06, 2/11 1.24, 4/11 3.81
Latest: 6 Corr Surgeries to Bladder Neck, SP Catheter since 10/1/9, SRT 39 Sess/72 gy ended 11/09, 21 Catheters, Ileal Conduit Surgery 9/10

compiler
Veteran Member


Date Joined Nov 2009
Total Posts : 7203
   Posted 5/15/2011 12:55 AM (GMT -6)   
I especially liked the comment at the end that this could lead to new therapies.
 
Probably 15 years down the road?
 
Mel

tatt2man
Veteran Member


Date Joined Jan 2010
Total Posts : 2842
   Posted 5/15/2011 4:13 AM (GMT -6)   
that sounds like a negative response compiler - so, in other words, why bother the research that can save lives and avoid unnecessary surgery?

Post Edited (tatt2man) : 5/15/2011 4:28:45 AM (GMT-6)


Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25380
   Posted 5/15/2011 8:06 AM (GMT -6)   
Bronson, it did sound like some bitterness or a barb in Mel's reply. I took it that way immediately.

It may or may not take long years for what could be accomplished, and even if it can reach "our" generation of PC guys, I would think we would all be eager to see help arrive for the next group down the line. Selfishness and bitterness get you no where in my opinion.

David in SC
Age: 58, 56 dx, PSA: 7/07 5.8, 10/08 16.3
3rd Biopsy: 9/08 7 of 7 Positive, 40-90%, Gleason 4+3
open RP: 11/08, on catheters for 101 days
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Incont & ED: None
Post Surgery PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12, 4/8 .04, 8/6 .06, 2/11 1.24, 4/11 3.81
Latest: 6 Corr Surgeries to Bladder Neck, SP Catheter since 10/1/9, SRT 39 Sess/72 gy ended 11/09, 21 Catheters, Ileal Conduit Surgery 9/10

compiler
Veteran Member


Date Joined Nov 2009
Total Posts : 7203
   Posted 5/15/2011 10:03 AM (GMT -6)   
David and Tatt:
 
Yes, I see where my comment could certainly be read that way. That's actually not what I meant.
 
Look, the name of the game for those of us with cancer is to get a cure now or, if we get beyond that chance, hopefully delay the beast until a cure comes along.
 
To my way of thinking, the most OPTIMISTIC part of the article for those of us who don't get a cure now is the idea that the results of this research will lead to a cure.
 
Yes, the idea of identifying whether or not a cancer is aggressive would be a HUGE move forward. In fact, the lack of such identification is perhaps the most frustrating aspect of getting a PC dx.
 
Even bigger would be a cure.
 
If this does lead to a cure (I know, that's a HUGE LEAP), how long would it take?
 
How long does it take from a lab breakthrough to an actual drug, in those few cases where they get an actual drug. How long did it take to develop Provenge or any of the other new drugs that seem to be coming out?
 
Mel

tatt2man
Veteran Member


Date Joined Jan 2010
Total Posts : 2842
   Posted 5/15/2011 1:52 PM (GMT -6)   
mel-
mel said...
Yes, the idea of identifying whether or not a cancer is aggressive would be a HUGE move forward. In fact, the lack of such identification is perhaps the most frustrating aspect of getting a PC dx.

that was my intent for posting this article.
BRONSON
New Topic Post Reply Printable Version
Forum Information
Currently it is Tuesday, June 19, 2018 6:31 AM (GMT -6)
There are a total of 2,973,221 posts in 326,155 threads.
View Active Threads


Who's Online
This forum has 160978 registered members. Please welcome our newest member, bobe54690.
369 Guest(s), 5 Registered Member(s) are currently online.  Details
Bull101, Sherrine, RobLee, iPoop, Lanie G