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ejc
New Member


Date Joined May 2011
Total Posts : 11
   Posted 5/20/2011 12:55 PM (GMT -6)   
I was reading some past postings & ran across the this subject.
Is it possible to control the spread of cancer at an early stage long term with this procedure?
 
Seems quite drastic but if it works....

Sonny3
Veteran Member


Date Joined Aug 2009
Total Posts : 2447
   Posted 5/20/2011 1:10 PM (GMT -6)   
To me, drastic would have to be in bold print, underlined and italics. Gotta say that there would have to be absolutely no options left.

But yeah, I guess it would help to control the cancer.

Sonny
60 years old - PSA 11/07 3.0 PSA 5/09 6.4
da Vinci 9/17/09 Post Surgery Pathology: GS 4+3=7
Stage: T3a
Tumor Volume 12.5% positive margin, extra-prostatic extension
PSA .6 IMRT completed 1/15/10 35 treatments- 70Gy
2/23/10 Post IMRT PSA 1.0
3/22/10 PSA 1.5
4/19/10 PSA 1.2
5/22/10 PSA 1.3
8/9/10 Radiation for MET
9/7/10 PSA 2.2
1/5/11 PSA 3.9
3/7/11 PSA 4.2
4/10/11 PSA 3.8
5/19/11 PSA 4.9

ejc
New Member


Date Joined May 2011
Total Posts : 11
   Posted 5/20/2011 1:12 PM (GMT -6)   
Sorry I left signature off of the initial post - again i am a newby.
 
I understand there would be long term issues but would it in essence starve the cancer?
 
1st psa ever Sept-2010 6.7, nerve spare robotic Nov-2010 (full easy recovery - no ill effects)
Gleason 7 (3+4), no lymph or seminal involvement, 2 very minimal surface spots
3 Mo. psa 0.05, 6 Mo 0.09

Sonny3
Veteran Member


Date Joined Aug 2009
Total Posts : 2447
   Posted 5/20/2011 1:15 PM (GMT -6)   
The purpose would be to stop the production of testosterone which feeds the PCa cells, the same as HT. This way it is just more permanent and finite.
60 years old - PSA 11/07 3.0 PSA 5/09 6.4
da Vinci 9/17/09 Post Surgery Pathology: GS 4+3=7
Stage: T3a
Tumor Volume 12.5% positive margin, extra-prostatic extension
PSA .6 IMRT completed 1/15/10 35 treatments- 70Gy
2/23/10 Post IMRT PSA 1.0
3/22/10 PSA 1.5
4/19/10 PSA 1.2
5/22/10 PSA 1.3
8/9/10 Radiation for MET
9/7/10 PSA 2.2
1/5/11 PSA 3.9
3/7/11 PSA 4.2
4/10/11 PSA 3.8
5/19/11 PSA 4.9

Cajun Jeff
Veteran Member


Date Joined Mar 2009
Total Posts : 4106
   Posted 5/20/2011 1:25 PM (GMT -6)   
In the years past that was standard procedure if PSA continued to climb after surgery and radiation. Before Lupron. We had a member last year on this board that chose to go that route.

Just a point of reference.

Cajun Jeff
9/08 PSA 5.4 referred to Urologist
9/08 Biopsy: GS 3+4=7 1 positive core in 12 1% cancer core
10/08 Nerve-Sparing open radicalSurgery Path Report Downgrade 3+3=6 GS Stage pT2c margins clea
r3 month: PSA <0.1
19th month: PSA <0.1
2 year PSA <0.1
Only issue at this time is ED but getting better

compiler
Veteran Member


Date Joined Nov 2009
Total Posts : 7203
   Posted 5/20/2011 1:27 PM (GMT -6)   
Does anyone know if the SE are less with the surgery??
 
Since the SE are mostly due to the lack of T, I would assume they are very similar.
 
If so, other than the cost and perhaps pain of the injection, I would still go with the Lupron with the idea/hope that down the road I could stop it.
 
Mel

Sagittarian
Veteran Member


Date Joined May 2011
Total Posts : 546
   Posted 5/20/2011 1:33 PM (GMT -6)   
If PCa needs male hormones to survive, and its absent
, couldn't it die off ??.  I think in addition to RRP, is whole lot
differerent than, intead of.  I think most of us would take this
over RRP, anyday.  I thought about this the same way you did,
very little mentioned about it anywhere.
DOB=DEC-1957, NJ, PSA HISTORY, FPSA=7%,
2002=1.83, 2006=3.18, 2007=3.09, 2008=3.20
2009=3.50, 2010=3.50, 2011=4.70, 2011=4.20
DRE, CT-SCAN, Bone Scan, =All Negative
BIOPSY, 12 Cores, APR 2011, 4 POS, 2(3+3), 2(3+4) All Left Side
% on POS 2(40%) 1(70%) 1(90%), PNI=Not observed

Da-Vinci Surgery=23 May 2011

F8
Veteran Member


Date Joined Feb 2010
Total Posts : 3800
   Posted 5/20/2011 1:51 PM (GMT -6)   
>>and perhaps pain of the injection<<
 
i'd be more concerned about the pain of getting my B**** cut off cool .  i had three shots of lupron and they didn't hurt, but the nurse took her time.
 
ed
 
 
age: 56
PSA on 12/09: 6.8
gleason 3+4 = 7
HT, BT and IGRT
received 3rd and last lupron shot 9/14/10
2/8/11 PSA <.1, T= 6 ng/dl

F8
Veteran Member


Date Joined Feb 2010
Total Posts : 3800
   Posted 5/20/2011 1:59 PM (GMT -6)   
Sag -- whichever form of castration you use -- chemical or surgical -- the cancer usually later becomes refactory.  i don't think there is any advantage to go the surgical route.
 
ed
 
 
age: 56
PSA on 12/09: 6.8
gleason 3+4 = 7
HT, BT and IGRT
received 3rd and last lupron shot 9/14/10
2/8/11 PSA <.1, T= 6 ng/dl

JNF
Veteran Member


Date Joined Dec 2010
Total Posts : 3744
   Posted 5/20/2011 6:58 PM (GMT -6)   
Ralph from Arizona checks in often. He had an orchiectomy in 1992 and continues to be undetectible. I do not know what his initial numbers were.

The side effects of ADT are not from the drugs, but from the resulting lack of testosterone.

This is a common treatment for testicular cancer, which is a young man's disease. Think Lance Armstrong. We should check in with men who have had the treatment at a relatively young age to see how they have done. Most likely they are not concerned about getting what we all have
PSA 59 on 8-26-2010 age 60. Biopsy 9-8-2010 12/12 positive, 20-80% involved, PNI in 3 cores, G 3+3,3+4,and 4+3=G7, T2b.
Eligard shot and daily Jalyn started on 10-7-2010.
IMRT to prostate and lymph nodes 25 fractions started on 11-8-2010
HDR Brachytherapy December 6 and 13-2010.
PSA <.1 and T 23 on 2-3-2011.
PSA <.1 on 4-7-2011
Second Eligard shot on 4-7-2011

F8
Veteran Member


Date Joined Feb 2010
Total Posts : 3800
   Posted 5/20/2011 7:19 PM (GMT -6)   
armstrong had one testicle removed.  he fathered his last two kids naturally.  LA says he often signs in at hotels as "juan pelota" cool .
 
ed
 
 
age: 56
PSA on 12/09: 6.8
gleason 3+4 = 7
HT, BT and IGRT
received 3rd and last lupron shot 9/14/10
2/8/11 PSA <.1, T= 6 ng/dl

Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25380
   Posted 5/20/2011 8:33 PM (GMT -6)   
No one is touching my jewel bag, cancer or no cancer.
Age: 58, 56 dx, PSA: 7/07 5.8, 10/08 16.3
3rd Biopsy: 9/08 7 of 7 Positive, 40-90%, Gleason 4+3
open RP: 11/08, on catheters for 101 days
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Incont & ED: None
Post Surgery PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12, 4/8 .04, 8/6 .06, 2/11 1.24, 4/11 3.81
Latest: 6 Corr Surgeries to Bladder Neck, SP Catheter since 10/1/9, SRT 39 Sess/72 gy ended 11/09, 21 Catheters, Ileal Conduit Surgery 9/10

Fairwind
Veteran Member


Date Joined Jul 2010
Total Posts : 3738
   Posted 5/20/2011 8:47 PM (GMT -6)   
It's cheap and effective, lowers testosterone to the absolute lowest level, has no drug SE....But it's PERMANENT..

Many men feel like Purgy...This guarantees the continuation of $2000 Lupron shots, which in many cases, are NOT as effective..The choice is basically a head game...

"Hormone Treatment" is seldom used as a PRIMARY treatment.. It is saved for LAST, when other less drastic forms forms of treatment fail...Unless of course the cancer is so advanced that other treatments would be ineffective..
Age 68.
PSA age 55: 3.5, DRE normal.
age 58: 4.5
61: 5.2
64: 7.5, DRE "Abnormal"
65: 8.5, " normal", biopsy, 12 core, negative...
66 9.0 "normal", 2ed biopsy, negative, BPH, Proscar
67 4.5 DRE "normal"
68 7.0 3rd biopsy positive, 4 out of 12, G-6,7, 9
RALP Sept 3 2010, pos margin, one pos vesicle nodes neg. Post Op PSA 0.9 SRT, HT. 2-15-'11 PSA 0.0

Post Edited (Fairwind) : 5/20/2011 9:14:43 PM (GMT-6)


Swimom
Veteran Member


Date Joined Apr 2006
Total Posts : 1732
   Posted 5/20/2011 8:59 PM (GMT -6)   
There is no assurance of preventing the spread of cancer but, there is a host of health problems associated hypogonadism.
I wouldn't suggest such a thing for early, low grade PCa.

Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25380
   Posted 5/20/2011 11:17 PM (GMT -6)   
agreed, swimom
Age: 58, 56 dx, PSA: 7/07 5.8, 10/08 16.3
3rd Biopsy: 9/08 7 of 7 Positive, 40-90%, Gleason 4+3
open RP: 11/08, on catheters for 101 days
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Incont & ED: None
Post Surgery PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12, 4/8 .04, 8/6 .06, 2/11 1.24, 4/11 3.81
Latest: 6 Corr Surgeries to Bladder Neck, SP Catheter since 10/1/9, SRT 39 Sess/72 gy ended 11/09, 21 Catheters, Ileal Conduit Surgery 9/10

Asp123
New Member


Date Joined May 2011
Total Posts : 3
   Posted 5/22/2011 7:08 PM (GMT -6)   
I'm 71 yr old who choose that route. Orcheietomy over lupreon was a no brainer.. Surgery took about 45 minutes and was not that big a deal at 71 years I'm not going to father children and fighting prostate cancer is the fight of a lifetime. My ultimate goal was to stop the matasisis from spreading further into my bones. Just had my first week for chemotherapy treatments and feel like crap. Anything to stay alive
Asp123
71 yr old recently diagnosed with bone matastised prostate cancer
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