A compound made from the bark of a cork tree ---- East Asian cork tree, Phellodendron amurense

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BobCape
Regular Member


Date Joined Jun 2010
Total Posts : 416
   Posted 5/27/2011 3:53 PM (GMT -6)   
Short article - just FYI....:
 
Scientists at the U.T. Health Science Center are studying a Chinese herbal medicine that may help prevent the recurrence and side effects of prostate cancer in men like Fitzgerald.
 
It’s a compound made from the bark of an East Asian cork tree, Phellodendron amurense. It’s sold in pill form as an anti-inflammatory. But early animal studies showed it shrunk tumors in mice.
 

geezer99
Veteran Member


Date Joined Apr 2009
Total Posts : 990
   Posted 5/27/2011 4:15 PM (GMT -6)   
A search on Medline gets nothing for Phellodendron amurense, the name of the tree, so this must be very preliminary research.
Age at diagnosis 66, PSA 5.5
Biopsy 12/08 12 cores, 8 positive
Gleason 3+4=7
CAT scan, Bone scan 1/09 both negative.

Robotic surgery 03/03/09 Catheter Out 03/08/09
Pathology: Lymph nodes & Seminal vesicles negative
Margins positive, Capsular penetration extensive Gleason 4+3=7
6 weeks: 1 pad/day, 1 pad/night -- mostly dry at night.
10 weeks: no pad at night -- slight leakage day/1 pad.
3 mo. PSA 0.0 - now light pads
6 mo. PSA 0.00 -- 1 light pad/day
9 mo. PSA 0.00 -- 1 light pad/day ED remains
12 mo. PSA 0.00 -- still one light pad and ED
16 mo PSA 0.00 -- light pad just for security, ED still an issue

BobCape
Regular Member


Date Joined Jun 2010
Total Posts : 416
   Posted 5/27/2011 4:21 PM (GMT -6)   
There is something about it coming out of nowhere that actually would get my spirits up. There seems to perpetually be several drugs that show hope. I/d always hoping for 1 that, out of nowhere, changes everything for all of us.

Todd1963
Veteran Member


Date Joined Oct 2008
Total Posts : 3218
   Posted 5/27/2011 6:17 PM (GMT -6)   
Dont whine about Pca. Put a cork in it. I can here the slogan now.
dx:06/03/06
Age at dx: 42 age now 45
Treated for sciatic nerve pain 6 months prior to dx.
Heavy amount of blood in urine Unable to urinate 
Lung x-ray for pnumonia revealed multiple lesions in each lung
P.S.A. at time of dx. 3216.14
Began lupron and casodex
Cat scan showed large mass in the pelvic area affecting the bladder multiple nodules in both lungs and lymph node envolvement.
Bone scan revealed possible bone involvment in the pelvic area
Biopsy 12 of 12 cores positive gleason 3+4=7
P.S.A.s since lupron 2946, 1274, 532, 5.01 1.23, .09
Begining jan 08 psa .o9, .25, .44, .86, .73, 1.34, 1.49. Doubling time is a little over 3 months
Cat Scan 12/12/08 Prostate normal size and shape. No tumors detected. Left lung clear of all nodules right lung showing only benign scar tissue. Lymph nodes normal
Bone Scan 12/24/08. Clean!!! went off casodex January 4 2009
Current psa 2/13/09 .16
Latest P.S.A. 0.05 newest P.S.A. undetectable

Todd1963
Veteran Member


Date Joined Oct 2008
Total Posts : 3218
   Posted 5/27/2011 6:24 PM (GMT -6)   
If it works the price will go up. I wonder if it is too late to buy stock in cork trees. Maybe I will grow some.
dx:06/03/06
Age at dx: 42 age now 45
Treated for sciatic nerve pain 6 months prior to dx.
Heavy amount of blood in urine Unable to urinate 
Lung x-ray for pnumonia revealed multiple lesions in each lung
P.S.A. at time of dx. 3216.14
Began lupron and casodex
Cat scan showed large mass in the pelvic area affecting the bladder multiple nodules in both lungs and lymph node envolvement.
Bone scan revealed possible bone involvment in the pelvic area
Biopsy 12 of 12 cores positive gleason 3+4=7
P.S.A.s since lupron 2946, 1274, 532, 5.01 1.23, .09
Begining jan 08 psa .o9, .25, .44, .86, .73, 1.34, 1.49. Doubling time is a little over 3 months
Cat Scan 12/12/08 Prostate normal size and shape. No tumors detected. Left lung clear of all nodules right lung showing only benign scar tissue. Lymph nodes normal
Bone Scan 12/24/08. Clean!!! went off casodex January 4 2009
Current psa 2/13/09 .16
Latest P.S.A. 0.05 newest P.S.A. undetectable

142
Forum Moderator


Date Joined Jan 2010
Total Posts : 6949
   Posted 5/27/2011 6:37 PM (GMT -6)   
And then more plastic corks and screw-tops for wine.

zufus
Veteran Member


Date Joined Dec 2008
Total Posts : 3149
   Posted 5/27/2011 8:23 PM (GMT -6)   
Bob- hope is eternal, keep hope alive, there are alot things having potential in diseases. Originally all our medicines came from natural resources, now some are man made and better living through chemistry mantra's.   (lol)
 
Gedunin is from a tree in India and has been found as a novel Hsp90 inhibitor, shown to manifest anticancer activity. (Journal of Medicinal Chemistry 2008). Hopefully someone will find out if it has value in PCa.

A drug used in kidney transplants, used commonly now in that proceedure and was FDA approved, comes from a fungus found only in the Easter Islands.....this is the twilight zone of medicine. (LOL) (a clue)

Post Edited (zufus) : 5/27/2011 8:35:08 PM (GMT-6)


Fairwind
Veteran Member


Date Joined Jul 2010
Total Posts : 3748
   Posted 5/27/2011 9:54 PM (GMT -6)   
Here is the compound that is extracted from the tree..

en.wikipedia.org/wiki/Hu%C3%A1ng_b%C3%B2
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