Pathology results ?

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EnglishBob
Regular Member


Date Joined Jan 2011
Total Posts : 126
   Posted 6/12/2011 7:20 AM (GMT -6)   
Hi everyone,

I have had a hell of a job getting my pathology results in writting, the UK health service does not like giving you information officially grrrr. I will type it all up in here and wonder if you more knowledgable ones can interpret it for me, official doctor type jargon is a nightmare .......

Additional tissue/organs macroscopy

Seminal vesicle (B) Dimension: 23 . 8 . 9mm
Specimen type Radical prostatectomy
Weight 51.3 grams
Size
Superior/inferior 50mm
Anterior/posterior 40mm
Medial/lateral 45mm
Connective tissue Not found
Surical incisions Not found
Right seminal vesicle size 30 . 7 . 9mm
Right seminal vesicle dimensions
Right Vas 20mm
Left seminal vesicles Not found

Blocks
A01=Apex Lt
A02=Apex Rt
A03-A08=Megablock
A03-A08=Prostate
A09=Right seminal vesi
A10-A14=Base Rt
A15-A19=Base Lt

Microscopy

Tumour volume 12%
Tumour site Base, Apex and both lobes
Histological type Adenocarcinoma
Gleason score 7 (3+4)
Multifocal Yes
Extent of invasion Confined to prostate
Vascular invasion Not found
Perineural invasion Not found
Associated high grade Pin Present
Margins involved No
Other histological features Chronic inflammation

Microscopy additional information
The tumour is very close to the apical margin (less than 1mm away) but NO actual margin involvement is demonstrated

Additional tissue/organs microscopy

Seminal vesicle (B) Metastic involement: Not found

Summary
Tumour type Adenocarcinoma
Gleason grade 7 (3+4)
Stage: pT2 pNX pMO (UICC:5th edition)

Completely excised at all margins


I have copied that all across EXACTLY as it is typed up in the letter, word for word, letter for letter. I hope it makes sense to one of you who can then explain it in English :))

Have fun and LIVE!!!!
The crazy English guy, Bob.
Age 59
Prostate problems since early 40s
Ed since early 40s
April 2007 biopsy & all clear
July 2010 prostate swollen more, psa up to 5.6 August 6.7
September, biopsy again
October 7th diagnosed prostate cancer, Gleason grade 6 at 10% mass
December 13th 2010 open Radical Proctatectomy (non nerve sparing)
Pathology results came back Gleason grade 7 at 12% mass BUT clear margins
Catheter out Jan 5th 2011
Caverject for penile therapy 22nd Jan 2011
Dry at night since 1st Feb 2011
Psa at 3 months post op is now 0.03
Dry in day and pad free from 16th April 2011 :))

knotreel
Veteran Member


Date Joined Jan 2006
Total Posts : 654
   Posted 6/12/2011 8:30 AM (GMT -6)   
I am sure there is lots of info there that went over my head but the "no" parts sound good! It looks like you have it out not a monent too soon as the tumor was only a mm away from margin? I think that report is what you would want. I hope your recovery continues.
Ron
06-08 1st biopsy neg psa 4
10-09 psa 5.5 2nd biopsy 1/12 pos. 10%, G(4+3) age 65
12-15-09 RRP Tulane NOLA Dr Lee
Path, 1%, clr marg, no EPE, no SVI, nodes cl, G(4+3)
100% incontinent @ 12 months
ED, pre-op severe, post op total
10/10 Dr Boone, Methodist recomended AUS
AUS/ IPP performed 1/11/11 Methodist Houston
post op psa's 0.04,<0.1,<0.1,<0.01@12 mo.

tarhoosier
Regular Member


Date Joined Mar 2010
Total Posts : 495
   Posted 6/12/2011 9:16 AM (GMT -6)   
Bob:
This is a generally good report. Your prostate was on the larger size of normal. There was no tumo(u)r at the margins. There was tumor extremely close to the margin near the apex (closest toward the penis in direction when looking from your eyes). There was some G4, percentage of G4 tumour not identified, though less than half of the cancer total since it is graded as G3 +4. Any G4 is of concern. 12% tumour involvement is certainly a significant amount. Only one Seminal vesicle found. Unclear if the other was removed or separated and lost, or not removed.
This is a generally full and complete report with no obvious omissions from the pathologist. I think that you can feel good about this report. The surgeon did as much as he could do and appears to have done it well. Same for the pathologist.

Sleepless09
Veteran Member


Date Joined Jul 2009
Total Posts : 1267
   Posted 6/12/2011 10:46 AM (GMT -6)   
Lots of great news. A couple off iffies ("iffies" being a techincial PCa term us Canadians use when discussing deep scientific matters.)

Bottom line: It says you one lucky "son-of-a-gun" -- that's what it says.

Sheldon AKA Sleepless
Age 67 in Apil '09 at news of 4 of 12 cores positive T2B and Gleason 3 + 3 and 5% to 25% PSA 1.5
Re-read of slides in June said Gleason 3 + 4 same four cores 5% to 15%
June 29 daVinci prostatectomy, Dr. Eric Estey, at Royal Alexandra Hospital Edmonton one night stay
From "knock out" to wake up in recovery less than two hours.  Actual surgery 70 minutes
Flew home to Winnipeg on July 3 after 5 nights in Ramada Inn  ---  perfect recovery spot!
Catheter out July 9
Final pathology is 3 + 4 Gleason 7, clear margins, clear nodes, T2C, sugeron says report is "excellent"
 
Oct 1st 09 -- dry at night, during day some stress issues.
Oct 31st padless 24/7 
 
First post op PSA Sept 09  less than 0.02
PSA on Oct 23, 2009 less than 0.02
PSA on Jan 8, 2010  less than 0.02
PSA on April 9, 2010 less than 0.02 
PSA on July 9, 2010 (one year) less than 0.02
  

BillyMac
Veteran Member


Date Joined Feb 2008
Total Posts : 1858
   Posted 6/12/2011 6:13 PM (GMT -6)   
Looks like you got through life with one seminal vesicle Bob, but that like bollocks, is all you need to do the job.

Superior/inferior ===== top to bottom size of the gland 40mm
Anterior/posterior ====== front to back size of the gland 50mm
medial/lateral ========size side to side through the middle of the gland

Surgical incisions not found I believe means the gland was removed intact without being cut into.

The blocks are simply the way the gland is sliced up into sections after being set in paraffin. There may be a drawing with the numbers and letters indicating where that particular block was located in the gland.

12% of the gland was tumourous with a Gleason score of 3+4=7. Sometimes the report will give the percentage of each.

The excellent news is clear margins (although close at one point) with the gland removed completely intact (great) and clear seminal vesicle. There was no sign of tumour in the blood vessels (vascular) and nerve system (perineural) within the gland (double great).

All in all a most excellent report.
Bill

Post Edited (BillyMac) : 6/12/2011 5:16:36 PM (GMT-6)


Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 25393
   Posted 6/12/2011 6:28 PM (GMT -6)   
Sounds like a very good pathology report to me. Hopefully you will do well from this point on.

david
Age: 58, 56 dx, PSA: 7/07 5.8, 10/08 16.3
3rd Biopsy: 9/08 7 of 7 Positive, 40-90%, Gleason 4+3
open RP: 11/08, on catheters for 101 days
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Incont & ED: None
Post Surgery PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12, 4/8 .04, 8/6 .06, 2/11 1.24, 4/11 3.81
Latest: 6 Corr Surgeries to Bladder Neck, SP Catheter since 10/1/9, SRT 39 Sess/72 gy ended 11/09, 21 Catheters, Ileal Conduit Surgery 9/10

EnglishBob
Regular Member


Date Joined Jan 2011
Total Posts : 126
   Posted 6/13/2011 4:08 PM (GMT -6)   
BillyMac said...
Looks like you got through life with one seminal vesicle Bob, but that like bollocks, is all you need to do the job.


Do you know, i never thought i might have had just one seminal vesicle, i just presumed they had left one behind
Age 59
Prostate problems since early 40s
Ed since early 40s
April 2007 biopsy & all clear
July 2010 prostate swollen more, psa up to 5.6 August 6.7
September, biopsy again
October 7th diagnosed prostate cancer, Gleason grade 6 at 10% mass
December 13th 2010 open Radical Proctatectomy (non nerve sparing)
Pathology results came back Gleason grade 7 at 12% mass BUT clear margins
Catheter out Jan 5th 2011
Caverject for penile therapy 22nd Jan 2011
Dry at night since 1st Feb 2011
Psa at 3 months post op is now 0.03
Dry in day and pad free from 16th April 2011 :))
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