Understanding my pathology report

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Leroy
Regular Member


Date Joined Jan 2009
Total Posts : 41
   Posted Today 4:11 PM (GMT -6)   
My pathology had two notes under "diagnosis."

"Revised report": adenocarcinoma with varying neoplastic glands, combined Gleason score 6 (3+3), involving 5% of tissue, one of two cylinders.

Then it says "Revised" previously reported as adenocarcinoma with varying and fused neoplastic glands, combined Gleason score 6 (3+3), involving 5% of tissue, one of two cylinders.

It later says "case was revised due to error in diagnosis"

Anyone have any idea what the difference means, the reference to "fused glands" was edited out. What does that mean? I guess it doesn't matter since it's been "corrected" but what did they think they saw before they changed it?
Age 60 PSA 2.7, DRE abnormal rt side, biopsy 6/9, 5 cores from rt side
Dx 6/15 - 1 of 5 positive, Gleason 6 (3+3), 5%, T2a
Cat scan being scheduled

Casey59
Veteran Member


Date Joined Sep 2009
Total Posts : 3172
   Posted Today 5:08 PM (GMT -6)   
Hi, again, Leroy.
 
Keep in mind that all my comments are made as a well-educated (school of hard knocks) patient with no medical training. 
 
One of the very important recommendations for newly diagnosed PC patients is to get a second opinion of their biopsy results, specifically an expert opinion from someone specializing in prostate biopsy.  Doctors are very used to this, and it happens all the time...you won't be hurting feelings asking for this.  There are several expert labs, and they are set-up to take 2nd opinion business.  Read THIS.
The more fusing of cells, the worse.  Fusing starts showing up in Gleason 3, and gets more prevelant in Gleason 4.
 
hope this helps...

tarhoosier
Regular Member


Date Joined Mar 2010
Total Posts : 486
   Posted 6/19/2011 9:36 AM (GMT -6)   
Leroy:
At this distance is is not possible to know what happened between the submission of the biopsy samples and the submission of the revised findings. I have a guess. Pathologists work under pressure with many tissue samples presented. The younger, less experienced doctors have their findings reviewed by their superiors. At least that is the theory and is best practice. It is possible that one pathologist made the initial findings and his colleague/mentor revised it after a second examination. Not that the first report was invalid, just that it did not follow the individual lab reporting standard and wording (possibly).
Discuss this with your urologist. Also I am unsure why a CT scan is necessary.

Leroy
Regular Member


Date Joined Jan 2009
Total Posts : 41
   Posted 6/19/2011 9:42 AM (GMT -6)   
@tarhoosier - I'm assuming the CT scan is because my prostate was enlarged on the right side, thus indicating the cancer was growing? Then they do the scan to determine spreading, if any, to lymph glands? That alone has me sleepless, as it's just one more "wait and see" situation.
Age 60 PSA 2.7, DRE abnormal rt side, biopsy 6/9, 5 cores from rt side
Dx 6/15 - 1 of 5 positive, Gleason 6 (3+3), 5%, T2a
Cat scan being scheduled
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