I had 3 biopsies, about a year apart..The first 2 showed no cancer..Then 9 months later, after PSA started climbing rapidly, 4 cores were positive, 2 G-6, one G-7, one G-9...Two months after that, the complete organ showed 7 separate and distinct tumors ranging from G-6 to G-9..
I hope you are not citing your case as proof that your cancer developed in one year. Your PSA history is telling. In all probability you had prostate cancer with a PSA of 3.5 at age 55 and your diagnosis at age 68 after using Proscar, was related to a reduction in gland volume that made the diagnosis easier.
If we accept that PCa is in general a slow growing malignancy that (because of this characteristic) allows men to to take their time to decide what to do, then this theory that PCa can develop in quantity and aggressiveness in a matter of one year, is a very negative proposition for those that support the slow growth nature of the disease.
Dr. Klotz who reports progression of PCa in men undergoing AS, believes that grade change within one year is caused by the original biopsy missing the cancer and not by a grade change. Further biopsies that identify a higher grade attribute the change to further dedifferentiation (grade increase).