Wow I just googled "effect of ejaculation before prostate specific antigen PSA test 24 hours 48 hours 72 hours" There were lots of studies! It is significantl
One Greek paper from Dept of Internal Medicne , Naval Hospital of Crete, Chania, Greece,
"We have examined a 52-year-old asymptomatic Greek subject who in an annual routine blood test had a serum total PSA of 6 ng/ml. His personal and family medical history was unremarkable. There was no history of using drugs, or having symptoms of benign prostate hypertrophy, prostate cancer or prostatitis, and he had no recent diagnostic clinical tests of the genitourinary tract. The patient refused digital rectal examination. An abdominal and prostate ultrasound scan showed no evidence of benign prostate hyperplasia or of prostate cancer. Serum total PSA after ten days was 5.2 ng/ml, but the percent free PSA was 27% (normal > 20%) . After a month, serum total PSA value was 1.2 ng/ml. In another blood test after 3 months, serum total PSA value rose to 7 ng/ml with a percent free PSA of 40%. The urologist recommended a transrectal ultrasound-guided prostate biopsy. The patient refused biopsy. All serum PSA measurements were performed with the same radio-immune assay (RIA) in a nuclear medicine laboratory (Tandem-R PSA, Hybritech Inc., USA) with normal range 0-4.0 ng/ml. The percent free serum PSA was calculated as the ratio of serum free PSA to total PSA multiplied by 100. After discussing this situation with the patient, we were informed that he had sexual activity and ejaculation in less than 24 hours before the first and before the last serum PSA measurements (being 6 and 7 ng/ml respectively). Ejaculation might have had an effect on serum PSA levels in our patient. All other values of serum total PSA measurements performed at least 4 days after sexual abstinence were <1.2 ng/ml..
That's an extreme case. The guy ejaculated within 24 hours of test and had a PSA of 6. One month later it was 1.2. At 3 months he repeated the test after ejaculating within 24 hours and his PSA was 7!
I'd live to be a fly on the wall in that bedroom!
Age: 59, Mar 36 yrs, 56 dx, PSA: 4/09 17.8, 6/09 23.2
Biopsy: 6/09 7 of 12 Pos, 20-70%, Gleason 4+3 Bone, CT Neg
DaVinci RP: 7/09, U of Roch Med Ctr
Path Rpt: Glsn 3+4, pT3aNOMx, 56g, Tumor 2.5x1.8 cm both lobes and apex
EPE present, PNI extensive, Sem Ves, Vas def clear, Lymph 0/13
Incont: 200ml/day ED: Trimix
Post Surg PSA: 10/09 .04, 7/10 <0.01, 7/11 <0.01, 1/12 <0.02
AdV Sling 1/10/11 Dry