In the most recent blog posts at http://abiraterone.blogspot.com/ there is what purports to be an interview with Dr. Gerry Potter, the man who first synthesized abiraterone, now known as Zytiga. Those who don’t mind an extra mouse click can check here to see the full posting,abiraterone.blogspot.com/2012/10/exclusive-interview-with-prof-potter.html
but what alarmed me was the following:
“I'm set to receive royalties from the sales of Zytiga so it will be nice at long last to actually receive some financial reward for discovering this important anticancer agent. I knew when I first discovered Zytiga that it would one day become a blockbuster. The results were so good it couldn't fail. Extreme Potency. No toxicity. Very well tolerated so you cant go wrong. What more do you want, this is the perfect cure for Prostate Cancer.”
He calls it a cure? Did I read that right? Does the tone of this interview sound weird to anyone else? His attitude is much too dismissive of the fact that we still don’t know much about
Zytiga and how well it can work with different people.
In fact, earlier today, the blog posted some thoughts about
How Long Zytiga works. abiraterone.blogspot.com/2012/10/how-long-does-zytiga-work.html
The unnamed author admits that Zytgia doesn’t work in 20% of the people who take it. Further:
The longest Zytiga survivor is 8 years from the Phase I clinical trials in 2004.
There are several 6 year survivors still taking Zytiga from the Phase II clinical trials.
There are hundreds of 4 year survivors on Zytiga from the 1000 cohort of the Phase III trials.
In my mind, this doesn’t constitute a “perfect cure for Prostate Cancer”! A perfect cure would be an drug that makes your cancer go away and it doesn't ever come back as long as you live!
The posts are interesting nonetheless. However, the blog in general has a snarky tone when talking about
Xtandi and Provenge, as if it's trying to sell to the investors rather than communicate with the people who actually have the disease.
Diagnosed 9/14/2011; Age 47; PSA 5,000+
Metastatic Stage 4, spread to entire skeleton w/femur fracture
Current therapy: Lupron/Casodex/Aredia
June 4, 2012: PSA 2.2, doing well with little discomfort
June 27, 2012: PSA 1.42
July 24, 2012: PSA 0.69 !!!!!
September 25, 2012: PSA 1.2 (Oops)
October 11, 2012 PSA 1.4 (not good)