PNI a clarification Tall Alans point. They are cancer cells occupying the space around the tiny nerve strands within the prostate. Not to be confused with the nerve bundles on the side that function erections. Though these nerve bundles are favorite place for apex tumors to go in an EPE. This is why nerve bundles are taken if it looks suspicious, rather than teased away in nerve sparing op.
On another point, the study, if Peter is correct about
zero follow up and I sense he is, proves nothing about
migration as migration takes time. Migration, makes perfect "common sense" to me and feel it is wishful thinking to think it does not exist. The study does in fact make a strong case that gl 6 does not easily make its way to lymph nodes. The other route to organ metastazation, blood streams, is hampered by the " out of the womb too early syndrome", for gl6 cells, hence diminished survival capacity. This all bodes well with GL sixes
But the migration issue is not going away in my opinion. just to be clear, by migration, I do not mean metatzation, i mean migrate to a higher gleason.
Diagnosed 8/14/09 psa 8.1 66,now 69
2cores 70%, rest 6-7 < 5%
gleason 3+ 3, up to 3+4 @ the dub
RPP U of Wash,
pathology 4+3, tertiary5, 2 foci
extensive pni, prostate confined,27 nodes removed -, svi - margins -
99%continent@ cath removal. 1% incont@gaspass,sneeze,cough ED penatration at 2 years with cialis/viaga. < .1 at 33 mod < 0.1 @ 39mos
Post Edited (logoslidat) : 4/2/2013 3:11:46 PM (GMT-6)