I'm happy about
a really terrible number!
I just had my testosterone and PSA checked after 7 weeks on Lupron monotherapy, before starting radiotherapy next week.
My testosterone is less than 20 ng/dL, so well below castrate level. Yay! Now how can I be so excited about
such a terribly low number? Only people on this forum can appreciate that!
On the other hand, my PSA is 2.0. Now, I'm not sure if that's good or not. It was 5.2 on Mar 15 before diagnosis, and was 9.67 about
3 weeks after my April 15 biopsy (so maybe artificially elevated?). My testosterone level then was 440.
So, is this PSA drop in 7 weeks with my drastically lower testosterone expected, sufficient, or not? I was mainly concerned how hormone-sensitive my PCa is, and have read a paper saying best outcomes with RT happened when people had a pre-RT PSA of less than 0.5 (google: "PSA response to neoadjuvant androgen deprivation therapy is a strong independent predictor of survival in high-risk prostate cancer in the dose-escalated radiation therapy era."). Obviously, I'm way above that, so maybe it's not so hormone sensitive, or else it takes more time to respond to the loss of testosterone.
So, should the RT be delayed to get the PSA level lower? Or, at least see the trend? Or, just plow ahead with the treatment schedule? I'll ask the RO, but they didn't really seem to care much about
it. The tests were done because I asked for them, not pushed by my RO. He said go ahead and have them done wherever it was convenient for me. We never talked about
any impact to the treatment plan.
The funny bit - so I had the blood tests done through my GP's office. Apparently they haven't been kept up to date by my Vanderbilt team that I'm on a PCa treatment trajectory. The GP's office called me this morning rather alarmed about
my extraordinarily low testosterone level, and wanted me to come in right away to see them! I said, "No, that's great news, and thoroughly expected from Lupron therapy!". She said she would let the doctor know. :)
Post Edited (Redwing57) : 6/19/2013 9:41:32 AM (GMT-6)