Thanks Alf for the link. An interesting twist is the conclusion of this (very confusing) study and something we have not heard before - not in these words: Screening too young - below 45 years of age - detected too few deadly cancers.
And delaying screening until after a man's 50th birthday missed too many.
Screening men at the age of 45-49, however, spotted nearly half (44%) of the cancers that went on to be deadly.
From what I am reading, the other significant predictor group is 50-55. Also, the authors quote their previous study that says PSA concentration at 60 was strongly relevant to the risk of death at 85.
My take on this, very important to have the first PSA at 45-50 and if it is above median 0.68 ug/mg keep a close eye, if it is below relax, but not entirely, as even some guys below the median value at 45-50 went on to develop metastatic cancer after 25 yrs. And continue doing screening till 70. I guess nothing we didn´t already know. :)
Father diagnosed in Jan 2011 (at age 68):
DRE positive, PSA 7.5, biopsy Gleason 7 and 8.
two inconclusive bone-scintigraphies, MR scan showed 2 bone mets
1-Feb-11: Started hormonal therapy (Trelstar+Casodex)
2-Feb-12: last Trelstar injection
Post Edited (SpecialLady) : 4/17/2013 1:14:45 PM (GMT-6)