Mel….My side effects started about the 4th month
with hot flashes. This was just after my 2nd 22.5mg 3-month Lupron
injection. Every month from there, additional side effects along with the
severity have increased.
PeterDisAbelard, Michael, and Southern Comfort…..I really
appreciate you giving me some insight and advice based on your experience.
Thanks very much. The best way to sum it up appears that I need to stay the
course until it gets totally unbearable.
Here is a bit more detailed info with regards to my
experience with the evil witch concocted drug called Lupron:
I’m experiencing all the typical side effects of ADT therapy
with the exception of enlarged breasts. Hot flashes (40+/day), loss of muscle
mass and weight gain (Despite strength and aerobic training 4 times/week.), total
loss of libido, bone density loss (Despite Vitamin D and Calcium supplements.),
joint pain, periodic cognitive issues, insomnia, fatigue, and depression.
No issues with ED until October 2012, then completely lost
all ability to get an erection. Radiation oncologist suggested that it was IMRT
related and prescribed PDE5 oral meds. Daily 5mg Cialis, 100mg Viagra for
intercourse, and use of VED for “penile rehabilitation”. No response initially,
but ability has begun to return after 6 weeks.
It's now May 2013, and my PSA continues to drop. 0.01 with T
of 12.8. ED and depression are still an issue, but it is getting better. Still
using daily 5mg Cialis, but have added weekend 20mg Cialis, and 200mg Viagra
along with daily VED use. This still allows Mr.Happy to come out to play but
requires very precise prior planning. My counselors and psychiatrists are
working wonders. The anti-depressants of Wellbutrin, Zoloft, and Trazodone are
certainly help too. I now feel like I have more energy despite ADT!!! Urologist
has also put me on monthly Xgeva injections to combat bone density loss and I
am tolerating that very well.
DX Dec 11: 54, POS DRE, PSA 1.6; PSA 09 0.08
BX: 5/12 POS 14-46% all GS 4+5=9
BS & CT SCAN NEG
DX: T3b ADT & IMRT
Jan 12: Lupron 3 yr w/1 mo Casodex
Mar 12: IMRT
Apr 12: PSA0.16 T8.5
May 12: END 45 IMRT (81Gy-Tomo)
Jul 12: PSA0.10 T13.5 Sep 12: PSA0.04 T5.4 Nov 12: PSA0.04 T2.5 Jan 13: PSA0.02 T11.5
Mar 13: Xgeva Apr 13: PSA 0.01 T12.8
ALL SE w/ADT. ED OK w/PDE5. VED for rehab. Depression.