Here we go said...
My husband is gl 9. Psa 0.1 after 1 year HT.
I wonder if other gl 9 think their psa will do anything but rise as soon as they stop HT, whether they were on it for 1 or 2 or 3 years.that is if not resistant before that time.
I'm on ADT2 for 2 years, it appears. My IMRT primary therapy is happening now. So, at the end of therapy they'll check PSA again, at some interval not yet defined. I'm hoping the PSA is "undetectable" at that point, and stays that way with quarterly PSA checks until the 2 years is up.
After the 2 years, we stop ADT2 and watch the T and PSA levels. Happy scenario, T goes up and PSA stays low forever. Less happy scenario, T goes up and PSA goes up. If that happens, I'll be on ADT forever. Much less happy scenario, PSA goes up while on the first series of ADT.
Personally, considering how much 5+4 and 4+5 I have, and that my PSA didn't drop nearly as fast as my testosterone level did during my initial ADT, I have to admit a little pessimism about
just how hormone sensitive my bad little cells are. Hopefully, any non-hormone-sensitive ones are still right in and around the prostate and the radiation treatments will cook 'em.
But yeah, I think there's at best a 50/50 chance of stopping the rise of my PSA after HT.
IGRT by IMRT started 6/26/13: 50.4 Gy pelvic nodes, 79.2 Gy to prostate
CAB: Lupron 5/1/13 (2 yrs), +Casodex 6/25/13 (1 yr? 2?)
Bilateral EPE per 3T MRI, but SV and LN "normal"
Age 55, Dx 4/16/13
Bx w/12, one side all G9=5+4 (80%, 60%), 4+5 (2 at 100%, 80%, 10%), PNI confirmed
Date PSA fPSA
3/13 5.2 12% PCA3=31
9/12 4.1 15%
history... since 2002 high/varying PSAs, incl 3 neg biopsies