"7/13 samples are positive for prostatic adenocarcinoma (4+3) , all on the left. Right is clear. 62mm total."
The total length of cancer in the 7 cancerous cores was 62 mm. It probably also told you the the percent cancer in each of those cores. "*High Grade Prostatic Intrapithelial Neoplasia = Absent*
This is confusing because I understand PIN to be a precursor of adenocarcinoma. If this understanding is correct, then this is a sample error. Given the finding of carcinoma, it is irrelevant. "
High Grade PIN is not always present. It can be a precursor, but doesn't have to be. Or they may have included it in the Gleason 3s."* Perineural Invasion = present.*
I understand this to mean that the samples include nerve fibres and that the cancer has invaded at least one of the samples. This raises the probability of post-RP recurrence."
True. It also raises the probability of seminal vesicle invasion, positive margins and lowers the probability that can do nerve-sparing."* Periprostatic Adipose Tissue Invasion. PAT is present but invasion is not identified.*
NOW I'm confused. How is this judgement different from the "present" perineural invasion and the "absent" finding of the previous two issues?"
They found a layer of fat surrounding your prostate, but didn't find any tumor cells in it. The fat increases the risk of positive surgical margins if you chose RP. It may be masking extracapsular extension or invaded lymph nodes.
Everything else you described looks right. Did you go over this with your urologist? What did he say?
What was your Gleason score, and highest % positive core? You'll also need to find out your prostate volume and have a PSA history. With that in hand, you can fill out a nomogram like the one below to find out what the average risks are for someone with your values:nomograms.mskcc.org/Prostate/PreTreatment.aspx
Allen - not an MD
•PSA=7.3, prostate volume=55cc, 8/17 cores G6 5-35% involvement
•SBRT 6 year results
treated 10/2010 at age 57 at UCLA
•PSA since treatment:
1/11:3.9 5/11:3.0 8/11:3.7 5/12:1.2 9/12:1.3 5/13:0.4
• SEs of treatment:
after 2 wks: mild urinary & rectal - last 1 wk
1 yr after: mild urinary - last 2 months