Posted 10/11/2013 4:49 PM (GMT -6)
His Gleason 4+3 is borderline aggressive, but with his PSA being so high it puts his in the high risk group even as a Gleason 7. While I'm not sure how it might alter this treatment, you could always get a second read on his biopsy slides, which is common advice here at HW. The sticky at the top of the list will give you information for Bostwick and Epstein, which are considered the two best at reading PC biopsy slides.
Zytiga is indicated for PC once the cells have grown resistant to HT. In my case, I'm taking it now as part of my HT as my oncologist (Dr Lam) feels some of the early clinic trials are promising in this regard. Although you don't say where you're being treated, you may also want to contact an oncologist that specializes in prostate cancer as they are familiar with the latest research and techniques. There are not many prostate cancer-specific specialists around, but there are a few...hopefully one is near you, but if not many will consult over the phone. I use Dr Lam here in Los Angeles (as do many others here at HW) and he has been a fantastic resource.