We're still trying to decide if husband should go with ART in January. I keep asking doctors if his high tumor volume (60%) increases his risk of BCR...none of the doctors have payed much attention to that. Then I found this study in latest issue of Uro Today. Relevant portions below:
The 5-year recurrence-free survival rates of pT3a diseases with negative surgical margin were 85.2% for percent tumor volume ≤ 12% and 57.7% for percent tumor volume >12% (P < 0.001). Patients with pT3a with negative surgical margins and percent tumor volume >12% showed comparable 5-year recurrence-free survival rate compared with those with pT3a with positive surgical margin (57.7% vs 57.6%; P = 0.763).
CONCLUSIONS: Despite having less impact on recurrence than other clinicopathological variables in pT3-T4 prostate cancer, percent tumor volume can further improve recurrence risk stratification in pT3a diseases with negative surgical margins.
Might help someone else going through the decision-making process.
Husband 63 at diagnosis 7/13
PSA 6.3. 12/12 cores positive, G7 (4+3)
RP 09/13: LN-, SV-, Margins-, EPE+ (Focally present right)
Prostate size: 15 grams. Tumor 60%
PSA 6 weeks post surgery: <.02
Post Edited (acsd) : 12/24/2013 6:40:09 AM (GMT-7)