Jack, did you phase down from 6-month shots to more frequent/ lower dose as you got closer to starting IHT?
Probably a moot point for me since I have been given a life sentence, but then I read about
successes for other met guys like JerryL, so who knows.
Knock on wood, at present other than a total loss of libido, no side effects, so not panicking about
when I can go on IHT. The only good thing about
having no libido, you don't think about
sex so not even aware any more of what we are missing.
I have read of others trying to get the last few shots to have a lower half-life.
With respect to the original post, there is no set timeframe. The initial target time varies by type of treatment and it gets adjusted anyway based on how well or poorly the Lupron effectiveness is.
edit - alephnull, I now see you are also G9 (4+5) with lymph invovlement vs. my Oligometastsis, plus 10 years younger. So depends on your onco whether you are advised it's OK to go onto IHT, or not. Good news is you are also respondiong well to 4-month Lupron.
I have an upcoming June 5th initial appt with Scholz/Lam/Turner in Marina del Ray CA as I am passing through on my way to spoil grandkids in San Jose for month of June. So we'll see what they have to say both about
IHT and about
whether I am being too timid on combatting G9 with mets using only Lupron and Xgeva, not even triple blockade yet and so far not even Casodex or Avodart to prevent potential initial flare.
Not even sure Zytiga or Xtandi or Provenge is an option pre-mCRPC, unless done as part of a clinical trial. Ditto for clinical trials seemingly not available while responding well to Lupron for over a year.
My medical onco at UF & Shands is old school milk one remedy at a time as long as we can and keep the powder dry for future battles. I think Scholz and Myers et al are on the other end of the spectrum, as well as knowledgeable posters like Tall Allen, SteelGuy and others.
I remember talking to Ralf of a Wed night chat a couple months ago but can't recall which side of the discussion he was on, I believe cocktail approach. I think there are more of the kitchen sink opinion than the don't mess with success guys (and gals like Wampuscat and WorryWart).
Jack edited while I was editing and looks like he agrees with being uber aggressive.
No way of knowing in advance how long before mCRPC so no right answer as both opinions have their own merits. So just listening at this point.
65 - DX 64 2/13 PSA 3.68 (6 mo doubling) Gleason 9 (4+5)
T1CN0M1B stage IV w. 7 of 12 cores worst ones 70% right PNI
oligometastatic 5 tumors 1 right sacroiliac, 2 on
T4 & T9.
1st Lupron 4 month 3-28-13, 2nd Aug 1
PSA down was 3.68, 0.68 on 08-08-13
PSA 0.12 02-11-14, T<3,freeT<0.048
Prostate shrunk from 50.4 to 31.6
UF & Shands treating w curative intent, not just palliative.
Post Edited (LupronJim) : 5/1/2014 7:34:31 PM (GMT-6)