Break60: I'm back on T supplementation because I think its prophylactic in my case. I stopped injections 18 months prior to my G9 Dx and went onto Caps and Gels for supplementation. During this time my T was always very low, almost as if I was not supplementing and my PSA Spiked.
Conclusion: Low T caused my PSA to increase. High T causes a saturation point and it does not effect my PSA; so I'll continue. see www.europeanurology.com/article/S0302-2838%2813%2900843-9/fulltext/a-new-era-of-testosterone-and-prostate-cancer-from-physiology-to-clinical-implications
Nebido (the maker of Testosterone andecanoate) also published a paper. I'm always a bit sceptical in cases where the vendor says their product is good and its supported by research. They say "Provocative new research suggests that it is not high serum T that is problematic for PCa, but to the contrary that it is low serum T that is associated with worrisome cancer features and outcomes, in that androgens promote less aggressive PCa phenotypes and inhibit metastasis of established PCa." see www.nebido.com/testosterone-and-prostate-cancer-a-paradigm-shift
I agree, because it was during LOW T, that I started having problems. I dont want to generalise these finding to anyone else, this is MY situation (subjects n=1) and it seems to work at the moment. I've been supplementing at 3 months post my RRP, because my PSA consistently came in as PSA < .010!
Again, thanks for the good wishes!
DX 9/13 Age 58
Gleason 9(4+5) 1+/16cores
pre-Op PSA 3.7 (08/13), 2.4(03/12), 1.9 (12/10), 1.6 (12/09) -- 0.8 (03/04)
RRP 10/13, Left Nerve sparing, pT2a
no Mets, clear lymph node & seminal vesicles
post-op PSA < 0.01 (11/2013, 01/14, 02/14, 04/14, 05/14, 09/14, 10/14)
ED - PDE5i, TRIMIX (ATO 52mcg, Phen 0.9mg, Pap 26 mcg) from 05/14
Testosterone undecanoate injections
Post Edited (PSA3DOT7) : 10/9/2014 11:05:33 PM (GMT-6)