I recently met with a new medonc who I like very much and has a great reputation in the community. He wants me to start monthly injections of Xgeva to prevent bone loss due to triple ADT and the effect it has on bones. My recent bone scan showed improvement from my initial scan back in March and noted a favorable response to treatment. Bone density test came back with results that were better than normal with no risk of fracture.
I'm concerned about possible side effects of Xgeva, can anyone share their experience with this drug and should I be concerned with this recommendation?
I want to aggressively treat my G9 PCa and if Xgeva will help prevent future mets and is wise due to the triple ADT and its effect on bone than I'm all for it. I would appreciate your thoughts.
First injection is scheduled for October 17th so I'm doing my homework before starting treatment.
9/14 0.1 T <20
7/14 0.2 T 33, DHT <5
Lupron/Casodex on 3/14, & metformin 7/14, Avodart 9/14
9/14 IMRT to prostate and pelvic nodes
Since 2006 high/varying PSA, 2 neg bx 2006 and 2008. 2nd bx normal - inflamation thought to be prostatitis
Dx 3/2014 age 55
Bx 9 of12 were pos, 5 - G9 4+5(100%, 80%, 70%), 2 - G8 & 2 - G7
Mets - spine, pelvis, ribs, nodes