Allen, good topic. This Scandinavian study could interest you: "Surgery Versus Radiotherapy for Locally Advanced Prostate Cancer (SPCG-15)". /clinicaltrials.gov/ct2/show/NCT02102477
To me it seems that surgery isn't proved to a bad option yet?
[quote]One potential advantage of adding prostatectomy to the treatment of locally advanced PC is that removing the prostate enables a full pathological assessment of the tumor characteristics and thus a better estimation of the risk of recurrence. Surgical treatment could thus reduce the numbers needed to treat with chemotherapy and radiation, and thus improve quality of life after treatment. In addition, evidence indicate that residual cancer in the prostate occurs in 25% after radiation treatment and surgical removal of the prostate may improve survival beyond what can be achieved by radiation and ADT. On the other hand, patients treated with surgery, radiation and hormones will experience side effects of all three treatment modalities and might fare better if radiotherapy plus hormones can provide oncological control without prior surgery.
Age at detection 60
PSA 4.1 2014-02-25
Biopsy 2014-04-24, 4 of 10 cores positive, G: 3+4,4+3,4+3 EPE,4+3
Bone scan negative,
DaVinci 2014-08-31, nerve sparing right side
Pathology: 35 g, 46x37x38 mm, no seminal vesicles involvement, 14 neg lymph nodes, neg surg. margins, pT3a, Gleason 4+3, EPE left side
2014-10-16 PSA <0.05
2015-03-04 PSA <0.05
2015-09-08 PSA <0.05