I've been wanting to contribute to this thread all weekend. Finally, I have some time.
So, in my understanding, cancer cells don't create out of thin air. First, there need to be some abnormal cells from which they will form. Much the same as an egg can produce a male or female, abnormal prostate cells can produce a cancer cell of a type specified. those specified PC cells have reproductive cycles specific to its type, with type 3 being the slowest of types 3, 4, and 5. 4 and 5 are more aggressive (faster to reproduce).
Type 3 reproduces in the range of 375 days. Doing the basic math, it takes quite a bit of time for type 3 to produce a mass that would pose a significant risk to the host, hence the urban label "30 year Cancer".
That is not to say, however, that type 3 doesn't spread given an appropriate amount of time without intervention.
Think of it this way, if a town population is small enough to live in 1 sq mile, and the reproductive rate of the population is such that no further town expansion is needed, (every day there is a new baby, an elder dies off) then expansion "spread' is somewhat doubtful, but in the case of a 2 to 1 or 4 to 1 ratio, then without intervention, expansion (spread) is a foregone conclusion.
Not a perfect analogy given other factrors, but close enough.
Age at DX 53
PSA 11/14=8, 11/15=11.5
DRE Nodule LHS LWR
22 Jan 2015, Biopsy 3 of 10 positive
3+3, 4+3, 4+4
Scans...NEG for METs
Triple Play Chosen (HT/HDRBT/EBRT)
Lupron Depot/Casodex 4 months base plan - Started 31st March
03/31/16 PSA=10.40, T=9.0
05/19/16 PSA=.64, T=<.6
HDRBRT 21/06/2016-16 Cath, 15Gy
EBRT started 05/07/2016-Tot 46 Gy, 4 Down...19 to go
NTAF MY FRIENDS!
Post Edited (Newton451) : 7/11/2016 10:09:34 AM (GMT-6)