I just talked to a friend in Seattle yesterday. He'd been diagnosed with one core with a small amount of GS 6, and was getting up at night to pee because his enlarged prostate. After a year on Avodart, he slept through the night. When he had his f/u biopsy (mpMRI-targeted) they found no
prostate cancer. A year after that, his urologist, determined to find his PC, gave him a transperineal template-mapping biopsy - he still found no
cancer (even though his prostate is much smaller and the cancer should be easier to find). His Uro told him to get a semi-annual PSA test and maybe they will talk about
another biopsy in 2-3 years. Of course, my friend is thrilled.
My friend's experience is not unusual. In one study, half of men on active surveillance who were taking Proscar or Avodart for an enlarged prostate had undetectable cancer on their next biopsy. (This compares favorably to about
30% undetectable on a repeat biopsy among men not taking the drug). These medicines are well known to prevent
low grade PC, and it may be that they may help get rid of some low grade PC as well. There's a lot more research that must be done to establish this, but so far, the effect is worth noting.
Allen - not an MD
•PSA=7.3, prostate volume=55cc, 8/17 cores G6 5-35% involvement
•SBRT 9 yr onc. results
•SBRT 7 yr QOL results
•treated 10/2010 at age 57 at UCLA,PSA now: 0.2,no lasting urinary, rectal or sexual SEsmy PC blog