If you have to show progression to get the scan, how can anyone on ADT not be hormone resistant? If so, I can see that a positive scan is more likely on ADT than not. An increasing PSA on ADT is a pretty clear alert signal. Am I misunderstanding?
I was not sure if the 68 Gallium PSMA scan would locate uptake of cancer cells while on ADT with low PSA. George answered that question.
So it would be possible to have a rise in PSA and then go on ADT and have PSA lowered. You would qualify for the trial even when the PSA decreases when you start ADT.
And, of course, if PSA is rising while on ADT the 68 Ga PSMA will detect where the cancer is.
Not sure Choline or other newer scans locate uptake while on ADT?
Age: 69, 69 at PC dx, PSA 6.7 Biopsy: 2/16 13 of 14 Positive, 2-99%, GL 7 (4+3) - RALP 4/20/16 Pathology:Non-Focal EPE, 2 positive margins, Gleason 4+3=7, involving 50% of gland, prostate weight 31.5 g, Stage pT3a N1, nodes 2/10, right side positive, Casodex 7/27/16, Lupron 8/17/16, uPSA 6/1/16, 2.41, PSA 6/16/2016, 2.6, 7/12/16, 2.2, 8/11/16 .6