Ran across this article for the second time and thought there may be some interest. Go to [CancerCommons.org]
I guess this is somewhat old news, however there are some on the board who feel they are running out of options.
Tall Allen did a very good post some time ago regarding Pembrolizamab ( Keytruda) It has become buried in the posts.
Please realize there are certain qualifications for the use of Keytruda and clinical trials regarding prostate cancer. Keytruda is approved for use in Melanoma. It has not to my knowledge been approved for prostate cancer.
Study Finds First Evidence That PD-1 Antibody Could Help Men with Metastatic Prostate Cancer
OHSU Knight Cancer Institute | Jul 13, 2016
“Restoring tumor-specific immunity is a treatment strategy that works well in melanoma and lung cancer patients. Now a new study out of the OHSU Knight Cancer Institute is reviving hope that the approach also may help men with life-threatening prostate cancer.
“It is a surprising turnaround because prior results in men with aggressive, advanced-stage prostate cancer showed no evidence of anti-tumor activity with immune therapies that work by blocking PD-1 signals.
“In the study published today in the journal Oncotarget, 10 men with metastatic prostate cancer resistant to androgen deprivation therapy and the androgen receptor antagonist enzalutamide were treated with pembrolizumab, a monoclonal antibody that binds to the PD-1 receptor.”
Go to full article.
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We sure can cure Pca in Mice!
Dx 1/17/13 Age: 66 Sta 4 8/8 cores positive GL 4+5=9
Failed Lupron 7/13.
Started Xgeva 12/13
Taxotere 10/13 (4) infusions
3/14 start Xtandi PSA < .01 till Jun. 2015 slow rise to 0.79
6/15 40 hits Proton
5/16 C11 pet scan -7 mets to bones 1 met to liver
6/16 started Jevtana/Carboplatin
10/16 PSA Plunged to 0.04
Add'l consult Dr. Kwon
Post Edited (RicktheRock) : 2/6/2017 9:55:05 AM (GMT-7)