Yes!! That was my story. I ride a lot of miles on my bicycle (2000 to 2500 a summer). Many autumns when I would have a physical my usual PSA of 1.9 or 2.0 would jump into the high 3 or low 4 range. I would do my 6 weeks of Cipro and it would go back to my normal. In 2011 after riding all summer my PSA in November was 5.2. Went on the usual Cipro for 6 weeks, but this time it only went down to 3.9. Urologist did DRE and found nothing and reccommended another round of Cipro. I actually said the heck with it and asked for a biopsy since in every other instance my PSA had always gone back to my normal. I just "felt" something wasn't right and wanted piece of mind. The rest is history.
Age:63 Diagnosis January 2012 Age 58
Original PSA Level 3.9 ......Gleason: 3+4
Biopsy results: 3 of 12 tested positive for cancer
Da Vinci Surgery 2/10/12
Negative Margins, cancer contained to prostate
Continent after 3 weeks
Sexual function fine with Cialis and now without meds at all
PSA undetectable for five years now.