Thanks all. I do hope the uPSA declines at the next test in 2 weeks time. Will update.
Allen, the links in your blog were very useful. The Kang study is particularly worrisome that any uPSA reading above 0.03 post RP implied 98% BCR, but I do realize that the cohort was PT3/4 and/or +ve margins, while I have favorable pathology. But it's unclear whether her conclusions on >=0.03 would also apply to patients with favorable pathology.
The Veseley study was also interesting to me mainly because they tested uPSA at 14 days, 30 days, 60, 90 and 180 days after surgery. Again this was a higher risk group than me with +ve surgical margins, but had a mix of lower risk patients as well although about
half had eventual BCR at 3-years. The 14 day BCR cutoff was not predictive but the rest were. Of interest were the 30 and 60 day cutoffs of .073 and .041 since I'm at 45 days with .050. It gave me some hope that the uPSA might fall between now and my retest, which will be 60 days.
Here's another study that uses uPSA <=0.05 as undetectable and has a 5-year follow up compared to the Veseley studies 3 years. Wonder what you think of it./www.ncbi.nlm.nih.gov/pmc/articles/PMC2930030/
Dx Age 55 Dec '16, PSA 4.33
MP MRI Jan '17: 1.9x1.1x1.2 nodule PI-RADS 5, Bone Scan -ve
Jan 17 MRI Fusion BX 4 of 12 cores positive G7 (3+4)
RALP Feb 2, 2017
Pathology: tumor 1.75x1.8x1.8 G7 (3+4), PT2c ECE, Margins, LN, SV all -ve
Post Edited (WeightLoss) : 3/20/2017 5:05:10 PM (GMT-6)