Hormone therapy is used in various situations and has different goals, depending on the situation. When used as an adjunct to salvage radiation, it has 3 goals:
(1) to radiosensitize the cancer
(2) to clean-up any additional hormone sensitive cancer cells
(3) to encourage an immune response
The duration of adjuvant ADT when used in conjunction with salvage radiation is a matter of some controversy. We know that 6 months is too little, and there's some indication that anything less than 12 months is too little. The exact duration will be based on your RO's assessment of what's probably needed. For example, if your DH had no positive margins, stage T3, predominant Gleason pattern 4 or 5, high initial PSA, and he treats with <70 Gy, he might recommend a longer duration. If there was a positive margin, stage T2, predominant Gleason pattern 3, slow PSA increase, and he uses 70+ Gy, he may recommend 6 months or no ADT./pcnrv.blogspot.com/2016/08/combining-androgen-deprivation-therapy.html
You cannot "only go to it if it proves necessary," if the goal is to cure him. This is for the same reason that you cannot take antibiotics for less than the full prescript
ion - doing so would drive resistance. ADT kills off only castration-sensitive cancer cells. If you leave any because you cut the ADT short, they will evolve into the castration-resistant type. You cannot stop and restart later. This is his last shot at a cure.
There are several treatments for hot flashes: estrogen patches, Megace patches, or aural acupuncture. Some guys prefer high dose bicalutamide instead of Lupron shots. Be sure to take 10 mg tamoxifen with that! The key is to drive the PSA as low as possible.
Allen - not an MD
•PSA=7.3, prostate volume=55cc, 8/17 cores G6 5-35% involvement
•SBRT 9 yr onc. results
•SBRT 7 yr QOL results
•treated 10/2010 at age 57 at UCLA,PSA now: 0.1,no lasting urinary, rectal or sexual SEsmy PC blog