In my opinion we have to be clear whether an early hormonal therapy might extend life, or not! Patrick Walsh, for example, thinks, that "So far, there has been no convincing scientific evidence to prove that early hormonal therapy prolongs life."...
Curious, when did he say that? Was it after
the results of the TOAD study? It is my understanding that the point of the TOAD study
was exactly that.
From the study:Immediate receipt of androgen-deprivation therapy significantly improved overall survival compared with delayed intervention in men with PSA-relapsed or non-curable prostate cancer. The results provide benchmark evidence of survival rates and morbidity to discuss with men when considering their treatment options.
Personally, I'm no fan of ADT having been on it for 3 years as part of my primary treatment. However, the usefulness of it seems quite clear. If and when it becomes my next step, I'll probably (reluctantly) do it.
[Edit: LowRoad, I noticed you are one of the few G9 5+4 folks here. I added you to the G9 Crew roster
; since you predated my time on this forum I missed your entry. You're one of the earliest in that subgroup. I've read some of your earlier threads, and you have had quite an interesting course of care. Thanks for your posts!]
Bx: 6/12 pos, G9=5+4 (80%, 60%), 4+5 (2@100%, 80%, 10%), PNI+
cT3a (3T mpMRI: Bilateral EPE, NVB+, SV-, LN-)
Date PSA fPSA
9/12 4.1 15%
3/13 5.2 12% PCA3=31
IGRT by IMRT, 44 done 8/28/13: 50.4 Gy pelvic nodes, 79.2 Gy prostate
ADT2 3 yrs: Lupron/Casodex, ended 3/16
Post: (age now 59)
PSA <0.1 : 8/13 - 5/16; rising - 0.2-8/16, 0.5-12/16, 0.7-3/17, TBD-5/17
Post Edited (Redwing57) : 5/8/2017 6:03:18 AM (GMT-6)