I'm glad he will be getting 72 Gy. That would be 40 treatments at 1.8 Gy each, so that makes sense. Here's why it's a good idea:
After you've read it, tell me what it is you don't understand. In simple terms, it says:
• 66 Gy is not enough
• For every additional +1 Gy, recurrence-free survival goes up by +2 percentage points
• So increasing the dose from 66 Gy to 72 Gy (+6 Gy) can reasonably be expected to increase recurrence-free survival from about
50% to about
• Acute grade 2 or 3 rectal toxicity was 17% at 64 Gy and 18% at 70 Gy in a randomized clinical trial - so, no difference among patients treated recently (since 2011).
With today's best machines, rectal toxicity is usually not a problem. It is not at all true
that fiducials are used with older machines. In fact, the use of fiducials with cone beam CT to use them with most likely means a very up-to-date machine is used there. The use of fiducials is controversial - some ROs use them with SRT, some prefer to align visually on soft tissue.
Allen - not an MD
•PSA=7.3, prostate volume=55cc, 8/17 cores G6 5-35% involvement
•SBRT 9 yr onc. results
•SBRT 7 yr QOL results
•treated 10/2010 at age 57 at UCLA,PSA now: 0.1,no lasting urinary, rectal or sexual SEsmy PC blog