The comment was made that Xtandi will not work when started after a run with Zytiga.
I did not find that to be true. My run with Zytiga knocked down my PSA significantly, but also wounded my liver pretty badly, so I was pulled off it, and the liver given a while to recover. After the (insurance) required three PSA increases, we went to Xtandi, which drove the PSA back down to below the best levels seen with Zytiga.
The Xtandi is starting to fail, but I'll stay on it until I can organize chemo. Due to some insurance coverage issues, that will be a couple of months at best.
But Xtandi after Zytiga has been a good run since April 2016.
If that is the option that works, give it a try.
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Moderator - Prostate Cancer(Not a medical professional)
IGRT journey (2010) - www.healingwell.com/community/default.aspx?f=35&m=1756808
HT (Lupron) 6-mo injection 9/12, 6/14 no more breaks, last 1/17
Prolia continuous 6-mo inj 12/12 to 6/17
Casodex started 12/14, end 3/15 after psa 30% rise
Zytiga 04-07/15 Xtandi 04/16-?