Posted 8/18/2017 3:14 PM (GMT -6)
I was diagnosed at 43, but it probably would have been picked up a year or two earlier, if the biopsy needle had hit the right spot. When I was in my late 30's, I noticed an uptick in nighttime urination. At 38, when I brought it up with my general practitioner, he performed a DRE. He said it was "boggy". He ordered a PSA. It was 4.5. He referred me to a urologist, who thought the prostate felt normal. He did a biopsy. Negative.
A year later my PSA was 4.1. 9 months after that it jumped to 6.1. The uro thought it was likely prostatitis and/or BPH, so he put me on Cipromax (a potent antibiotic) and high-dose Motrin. My PSA went down a bit, to 5.7. At this point I was 40 years old. T
4 months later, still on Motrin, my PSA jumped to 7.3. T he uro put me on Avodart--which at the time was thought to possibly have a preventative role in prostate cancer, and it would help with urinary issues. And he did another biopsy. This one was negative for cancer, but showed high-grade PIN.
Avodart has an effect on PSA independent of any role it might play as a preventive agent. My PSA fell to 2.2. But then it started creeping up, and when it hit 4.8 (effectively 9.6 because of the effect of Avodart), we did another biopsy and this one was positive.
So in short, my PSA was high for my age at 38, so maybe I had it all the way back then and we just kept missing it on biopsies--for 5 years. I do think my symptoms were more psychosomatic or related to some mild BPH and/or prostatitis. If I had been symptomatic all the way back then, five years later I would have been in big trouble. And I wasn't in dire straits at the time of dx. It was Gleason 3+4, 20% involved, not metastatic.
I'm doing fine now. Next month will be 10 years with an undetectable PSA.