I agree with Artist Mark (above) - it looks like the Lupron is depressing the PSA quite nicely, but as one who will also soon receive his first Lupron shot, I too am a bit curious about
the projected rate or slope of decline in PSA that the MO's typically hope-for from Lupron. You and I, we have chatted back and forth here a little bit before, because we share some similarities in our respective Dx's, but I can't recall whether or not you had ever been prescribed Casodex? I've been on Casodex myself now for just under 2-weeks, with Lupron soon to come, and its my understanding that MO's will often prescribe Casodex for a short (2-4 week) period, just prior to one's initial Lupron. Was that the case for you? I ask because I can't recall your exact circumstances and it doesn't appear in your signature.
In any event, Casodex alone has certainly worked for me. It has reduced my high PSA of 69 to just over 34 in less than 14-days, which I'm led to believe is a fairly impressive drop, and my RO has suggested that I continue on it for 10-14 days after my first 90-day Lupron shot, so maybe ask your MO about
Casodex? Perhaps it could/would augment or enhance the rate of decline somehow?
However, that said, my impression of your own reported PSA decline is that its probably a whole lot better than the value of the numbers alone might suggest, or than you or I might think. For example, if we were to imagine the PSA decline over time in roughly the same terms as the concept of PSA 'half-life', which is essentially the inverse or reciprocal of PSA 'doubling time' (i.e., the time required to double it or halve it), your PSA value has essentially been 'halved' TWICE in just 60-days. It dropped from 7.26 to 1.73 in just under 90-days, and if I understand it correctly, the Lupron was only on-board for 60 of those 90-days. So that's a drop from 7.26 to 3.13 (1/2), followed by 3.13 down to 1.56 (yours is just slightly higher at 1.73). but that's still down nearly another 1/2), all in just 60-days of Lupron. To me, that's an awfully decent drop in absolute value and an equally decent rate of decline. In fact, if I can ever get there myself, I'll be jumping for joy!
So, I think you're in great shape going into IMRT/Brachy, and I'll be following right behind you, starting both of those same two procedures, just 60-days later (LDR-Brachy ~ 9/20/18, IMRT ~ 10/20/18).
Good luck in July and beyond, and remember to stay positive!
Age at Dx: 65 (now 66)
Diagnosis (1/2018): High-Risk PCa
PSA (4/2017): 15
DRE (3x): Nothing found
Biopsy (1/2018): 6/12 cores '+' (5-65%)
GS-9 (Initial): 4+5=9, GS-8 (2nd Opinion): 4+4=8
PSA (3/2018) post-biopsy: 43
CT, Bone & PET Scans: No mets
3T-MRI: 1" dia. nodule right base (no lymph, but r-seminal vesicle involvement)
PSA (6/12/18): 69
ADT/HT: Casodex (6/13/18)
PSA (6/24/18): 34
Post Edited (Balladeer) : 6/27/2018 4:55:38 PM (GMT-6)