As an update, I met with my RO this week and developed a plan regarding my
Persistent PSA. Some others here have it and maybe this will help.
By way of review I've have little leakage over the last three months, my ED
symptoms are minimal, G 3+4=7 Grade Group 2, G pattern 4 = 10%, pT2c pN0 pMn/a,
carcinoma organ confined in about 15% of the gland, EPE SV LN
negative, PNI present, pathology verified by Dr. Epstein at JHMI. I did have one
small positive anterior margin 0.1 mm long and limited < .3mm.
My main concern is I've had ulcerative colitis for 45
years, and have had lower urinary tract symptoms (LUTS), a
group of clinical symptoms involving my bladder, urethra, urinary sphincter and
prostate for about 7 years. I had a TURP for
it one and a half years ago that didn't alleviate the problems at all.
So after two PSA's, both at .32 ng/mL, the alarms went off. I'll have
another PSA tomorrow and yet another in 4 weeks. I will also get another
Decipher Test; my first one was 15 months ago, and most importantly, I'll get an
Axumin PET Scan, also know as a Fluciclovine (18F), or
a anti-1-amino-3-18F-fluorocyclobutane-1-carboxylic acid(FACBC). It's
specifically for those of us with suspected PCa recurrence based on elevated PSA
Then in four weeks, I'll meet with both my RO and my surgeon, so
determine our next course of action. This also gives my system about four months
to recover from surgery.
My RO thinks I will need SRT and possible ADT. I'm going to
investigate SBRT clinical trials for persistent PSA, and what I'd really like is
some sort of active surveillance. Those RT side effects may be very
Some articles I found that talk about Persistent PSA
I hope the above helps some of you in the same boat.
70 years old @ Dx, LUTS for 6 years
PSA's never over 3.0, Now 2.3
Ulcerative Colitis since 1973
TURP 2/16, G3+4 discovered,
3T MRI fusion guided biopsy 6/16
14 cores; G 3+3, one G3+4, Grade T1b
Second 3T MRI 1/17
RALP 7/17 Dr. Gonzaglo The Univ of Miami
G3+4 Organ confined
pT2c pNO pMn/a
Mostly Dry so far
10 week PSA .32