From the medscape link in the OP:
Somebody said...
Over 10 years, statin use was linked to a 36% increased risk of being diagnosed with type 2 diabetes, falling to 27% after taking into account baseline risk factors and clinical criteria used to determine the need for statins.
The findings are consistent with previous studies suggesting that statin use substantially increases the risk of type 2 diabetes.
The new study was published online October 23 in BMJ open Diabetes Research & Care by lead author Jill P Crandall, MD, department of medicine and diabetes research center, Albert Einstein College of Medicine, New York, New York, and colleagues.
As previously reported by Medscape Medical News, a study of more than 8700 Finnish men aged 45 to 73 years showed that over 6 years of statins therapy were linked to a 46% increased risk of type 2 diabetes — more than double prior estimates.
This was followed by recent data from the Australian Longitudinal Study on Women's Health, which indicated that, among almost 8400 women aged 76 to 82 years, the risk of new-onset diabetes ranged from 17% with the lowest statin doses to 51% with the highest doses.
Despite accumulating evidence, the current researchers still maintain that the overall healthcare advice remains unchanged — the benefits of statins outweigh the risks.
So the 36% increased risk( or 27% if accounting for all baseline risk factors and clinical criteria used to determine the need for statins?) is apparently simply an additional increase in risk for people that are already at high risk? Is that correct? But when looking not at particularly high risk populations, just more the general populations that might need statins, the increased risk is more like 50%? Correct?
It is pretty darn impressive that the benefits outweigh the risks, considering all the misery diabetes can cause(just had a friend in his 60s who died a miserable death from it, but he also refused to do what was needed diet or meds for many years). Especially since those problems include a very significantly(2X-4X) increase in deaths fom CV disease.(and don't forget higher risk for amputations and blindness and many other problems, like many cancers and dementia) . But apparently the benefits do outweigh the risk. It appears we can increase the risk of diabetes a good bit and still end up better off after doing that. Definitely impressive indeed!
But taking statins along with their increased risk for diabetes(and for higher blood glucose leading to higher blood insulin I suppose?) for some possible slight improvement in my PC risk or outcome? Not me! (Many may well differ with me on that) I already have enough trouble staying away from diabetes due to my love of pancakes, bread, pasta and desserts! ( I guess there was a reason for the old name of sugar diabetes )