Not sure if this has been posted already, but I just ran across the article and thought this was worth sharing. It's generally positive, if somewhat cautious, towards SBRT.
The link is for a free full-text article. It has a lot of information, and as usual it's important to do your own research. I make no judgement, and am not vouching for any aspect of this article, just presenting it for information.
Here's the Conclusion
:Initial studies examining the use of SBRT in the treatment of prostate cancer have demonstrated impressive rates of biochemical recurrence-free survival and PSA response, while maintaining a relatively favorable acute toxicity profile. Doses of 8 Gy or less per fraction have lower reported rates of toxicity with similar biochemical control rates compared to higher doses per fraction. Though we are cautiously optimistic that SBRT has the potential to serve as an alternative to conventionally fractionated RT in the treatment of prostate cancer, long-term follow-up is needed in order to evaluate whether biochemical control, overall survival, and late toxicity are maintained, or improved, as compared to the current standard of care.Stereotactic radiotherapy for prostate cancer: A review and future directions
Bx: 6/12 pos, G9=5+4 (80%, 60%), 4+5 (2@100%, 80%, 10%), PNI+
cT3a (3T mpMRI: Bilateral EPE, NVB+, SV-, LN-)
Date PSA fPSA
9/12 4.1 15%
3/13 5.2 12% PCA3=31
IGRT by IMRT, 44 done 8/28/13: 50.4 Gy pelvic nodes, 79.2 Gy prostate
ADT2 3 yrs: Lupron/Casodex, ended 3/16
PSA <0.1 : 8/13 - 5/16;
steadying! - 0.2-8/16, 0.5-12/16, 0.7-3/17, 0.8-5/17, 0.8-7/17, 0.7-10/17