The paper stated clearly that alcohol plays a causal role in cancers of the throat and neck, voice box, liver and colon, as well as esophageal squamous cell carcinoma and, in women, breast cancer.
For women, just one alcoholic drink a day can increase breast cancer risk, according to a report released in May from the American Institute for Cancer Research and the World Cancer Research Fund that was cited by ASCO. That report analyzed 119 studies, including data on 12 million women and over a quarter of a million breast cancer cases, and concluded there was strong evidence that alcohol consumption increases the risk of both pre- and postmenopausal cancer, and that drinking a small glass of wine or beer every day — about 10 grams of alcohol — increases premenopausal breast cancer risk by 5 percent and postmenopausal risk by 9 percent.
“The more you drink, the higher the risk,” said Dr. Clifford A. Hudis, the chief executive of ASCO. “It’s a pretty linear dose-response.”............Even those who drink moderately, defined by the Centers for Disease Control as one daily drink for women and two for men, face nearly a doubling of the risk for mouth and throat cancer and more than double the risk of squamous cell carcinoma of the esophagus, compared to nondrinkers. Moderate drinkers also face elevated risks for cancers of the voice box, female breast cancer and colorectal cancers......
The risk for heavy drinkers — defined as eight or more drinks a week for women and 15 or more a week for men, including binge drinkers — are multiples higher. Heavy drinkers face roughly five times the risk of mouth and throat cancers and squamous cell esophageal cancers than nondrinkers, nearly three times the risk of cancers of the voice box or larynx, double the risk of liver cancer, as well as increased risks for female breast cancer and colorectal cancer.
“If you look at these figures, you see alcohol is a contributing factor; certainly it has a causal role,” Dr. Hudis said.
The International Agency for Research on Cancer, which is part of the World Health Organization, first classified the consumption of alcoholic beverages as carcinogenic to humans in 1987, tying consumption to cancers of the mouth, throat, voice box, esophagus and liver, said Susan Gapstur, vice president for epidemiology at the American Cancer Society.
Since then, she said, more and more evidence has accumulated tying alcohol to a broader group of cancers, including colorectal cancer and, in women, breast cancer. A more recent I.A.R.C. report concluded that alcohol “is a cause of cancers of the oral cavity, pharynx, larynx, esophagus, colorectum, liver and female breast.” (The esophageal cancer is largely specific to squamous cell carcinoma.)
“The story of alcohol has been quite consistent and has been peeled away like an onion over time, and we’re continuing to learn more about the mechanisms involved,” Dr. Gapstur said. “We don’t have randomized trials, but sometimes when you start looking at the coherence of all the evidence, including the observational epidemiology, the lab studies, the mechanistic studies, you begin to see a picture and get more clarity.”
So, PC off the hook yet again? It appears PC does not gobble sugar like other cancers seem to, but rather prefers fat. Although, there is still the question of insulin vs PC, and more recently triglycerides, both of which are dramatically raised by sugar. But limiting specifically to the concept of PC cells loving sugar, we dodged the bullet. But have we done it again with alcohol?
But as far as other cancers go, am I committing an only slightly slower suicide- regarding most cancers other than PC- when I wash down my pasta and dessert(both sugar) with my Cab Sauv? They have already taken sex away from me, now this?
PSA 10.9 ~112013
Bx on 112013 at age ~65yrs, with 5 of 12 pos with one G9(5+4), 1 PNI, T2B.
RALP with lymph nodes at Vanderbilt 021914. (nodes clear, SV+, G9 down graded to 4+5, cut wide, but 1 tiny foci right at the edge of margin ) Pros. 106.7 gms!
At 15 months, not wearing a pad most days, mostly dry
PSA <.01 on 6/14 and all until 9/15 = .01, still .01 9/16, .02 on 3/17,6/17,10/17