Yes, a large prostate can generate plenty of PSA, and prostatitis can ramp that up even more. I hung my hopes on that even after I had my biopsy done, and my URO told me not to worry, that a prostate my size could easily generate my PSA numbers of almost 12. But alas, it did no good for me to have that hope.
PSA 10.9 ~112013
Bx on 112013 at age ~65yrs, with 5 of 12 pos with one G9(5+4), 1 PNI, T2B.
RALP with lymph nodes at Vanderbilt 021914. (nodes clear, SV+, G9 down graded to 4+5, cut wide, but 1 tiny foci right at the edge of margin ) Pros. 106.7 gms!
At 15 months, not wearing a pad most days, mostly dry
PSA <.01 on 6/14 and all until 9/15 = .01, still .01 9/16, .02 on 3/17,6/17,10/17
Post Edited (BillyBob@388) : 11/17/2017 3:45:03 PM (GMT-7)